ArticleGlobal spine journal2025
Prevalence and Risk Factors for Cervical Adjacent Segment Disease and Analysis of the Clinical Effect of Revision Surgery: A Minimum of 5 Years' Follow-Up.
Article in Global spine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- High rates of spin bias in systematic reviews regarding anterior cervical discectomy and fusionJournal of spine surgery (Hong Kong) · 2026Review
- Article
- Development and validation of a nomogram prediction model for assessing cage subsidence risk following anterior cervical discectomy and fusion.BMC musculoskeletal disorders · 2026Article
- Zero-profile devices versus traditional cage-plate systems for geriatric osteoporotic patients with cervical degenerative disc disease: a retrospective analysis of 190 patients.European journal of medical research · 2025Article
- Review
- Biomechanical comparison of multiple zero-profile systems in anterior cervical discectomy and fusion: a finite element analysis.Journal of orthopaedic surgery and research · 2025Article
- Is screw position a greater contributor to adjacent segment disease than plate-to-disc distance following anterior cervical discectomy and fusion?BMC musculoskeletal disorders · 2025Article
- Investigation of spinopelvic sagittal alignment and its correlations in asymptomatic pediatric populations.Scientific reports · 2025Article
- Comparison of clinical efficacy of posterior percutaneous endoscopic cervical discectomy versus unilateral biportal endoscopy key-hole techniques for cervical spondylotic radiculopathy: a retrospective study with 2 years.Journal of orthopaedic surgery and research · 2025Article
- Risk factors and treatment strategies for adjacent segment disease following spinal fusion (Review).Molecular medicine reports · 2025Review
- Development and validation of a predictive model for the risk of symptomatic adjacent segmental degeneration after anterior cervical discectomy and fusion.Frontiers in neurology · 2025Article
- Radiographic Risk Factors for Adjacent Segment Disease Following Anterior Cervical Discectomy and Fusion (ACDF): A Systematic Review and Meta-Analysis.Global spine journal · 2024Review
- Anterior cervical corpectomy and fusion-derived adjacent segment disease managed via channel-repairing anterior endoscopic transcorporeal cervical discectomy: a case report.BMC musculoskeletal disorders · 2024Article
- Risk factors for poor neurological recovery after anterior cervical discectomy and fusion: imaging characteristics.Journal of orthopaedic surgery and research · 2024Article
- Comparative Analysis of Postoperative Sagittal Balance in Expansive Open-Door Laminoplasty versus Laminectomy with Fusion for Multilevel Ossification of Posterior Longitudinal Ligament: A Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designA retrospective study was performed.
objectiveTo investigate the prevalence and risk factors for adjacent segment disease (ASD) after anterior cervical discectomy and fusion (ACDF) and the clinical efficacy of revision surgery.
methodA total of 219 patients treated with ACDF were analyzed retrospectively. Demographic characteristics, including age, sex, body mass index (BMI) and bone mineral density (BMD), and radiographic measurements, including C2-C7 cervical sagittal vertical axis (cSVA), T1 slope (T1S), thoracic inlet angle (TIA) and C2-C7 Cobb angle, were analyzed. Modified Japanese Orthopaedic Association (mJOA) score and visual analog scale (VAS) score were used to evaluate patient function. Parameters were analyzed with Student's
resultsThe incidence of ASD after ACDF surgeries was 21%. The severity of osteoporosis, BMI and C2-C7 cSVA were significantly higher in the ASD group than in the NASD group (
conclusionPatients with a high BMI, severe osteoporosis, and a large C2-C7 cSVA after ACDF have a higher risk of ASD, while a large T1S and TIA may be protective factors. In addition, revision surgery can restore cervical spine balance in patients with ASD and promote better clinical outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.