Comparison of Illumination Methods for Flow-Through Optofluidic Biosensors.

Matthew Hamblin, Joel Wright, Holger Schmidt, Aaron R Hawkins

Abstract read

In one paragraph

Article in Micromachines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew HamblinElectrical and Computer Engineering, Brigham Young University, 450 Engineering Building, Provo, UT 84602, USA.

Joel WrightElectrical and Computer Engineering, Brigham Young University, 450 Engineering Building, Provo, UT 84602, USA.ORCID 0000-0002-2532-4429

Holger SchmidtElectrical and Computer Engineering, University of California, 1156 High Street, Santa Cruz, CA 95064, USA.

Aaron R HawkinsElectrical and Computer Engineering, Brigham Young University, 450 Engineering Building, Provo, UT 84602, USA.ORCID 0000-0002-3882-0771

Funding

Multiplexed, Non-Amplified, Nucleic Acid-Based Identification of Multidrug Resistant Pathogens Using an Integrated Optofluidic PlatformR01AI116989 · NIAID · BRIGHAM YOUNG UNIVERSITY · PI HAWKINS, AARON R., PITT, WILLIAM G · 2015 to 2019

$5.4M

Nanopore-based multi-target analysis of Zika virus infectionR01EB028608 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SCHMIDT, HOLGER · 2019 to 2022

$2.7M

NIAID NIH HHS R01 AI116989NIBIB NIH HHS R01 EB028608NIH HHS 1R01AI116989NIH HHS 1R01EB028608

6 · The paper itself

Abstract

Optofluidic biosensors have become an important medical diagnostic tool because they allow for rapid, high-sensitivity testing of small samples compared to standard lab testing. For these devices, the practicality of use in a medical setting depends heavily on both the sensitivity of the device and the ease of alignment of passive chips to a light source. This paper uses a model previously validated by comparison to physical devices to compare alignment, power loss, and signal quality for windowed, laser line, and laser spot methods of top-down illumination.

Indexed as

biosensorfluorescencelab-on-a-chipoptofluidic

Identifiers

PMID37420956

DOI10.3390/mi14040723

PMCPMC10142587

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.