ArticleSensors (Basel, Switzerland)2023
Split-Belt Treadmill Adaptation Improves Spatial and Temporal Gait Symmetry in People with Multiple Sclerosis.
Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Transcutaneous electrical nerve stimulation enhances locomotor adaptation savings in people with multiple sclerosis.Brain communications · 2025Trial
- Weight-bearing symmetry changes after asymmetric surface stiffness walking.Journal of neurophysiology · 2026Article
- Locomotor adaptation on a split-belt treadmill: mechanisms, modulation, and clinical utility.Journal of neurophysiology · 2026Review
- FedMedSecure: federated few-shot learning with cross-attention mechanisms and explainable AI for collaborative healthcare cybersecurity.Scientific reports · 2025Article
- Bidirectional locomotion induces asymmetric limb adaptations.Journal of neurophysiology · 2025Article
- Interhemispheric inhibition and gait adaptation associations in people with multiple sclerosis.Experimental brain research · 2024Article
- Propulsive Force Modulation Drives Split-Belt Treadmill Adaptation in People with Multiple Sclerosis.Sensors (Basel, Switzerland) · 2024Article
- Walking performance differs between people with multiple sclerosis who perform distinct types of exercise.Neurodegenerative disease management · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Multiple sclerosis (MS) is a neurodegenerative disease characterized by degradation of the myelin sheath resulting in impaired neural communication throughout the body. As a result, most people with MS (PwMS) experience gait asymmetries between their legs leading to an increased risk of falls. Recent work indicates that split-belt treadmill adaptation, where the speed of each leg is controlled independently, can decrease gait asymmetries for other neurodegenerative impairments. The purpose of this study was to test the efficacy of split-belt treadmill training to improve gait symmetry in PwMS. In this study, 35 PwMS underwent a 10 min split-belt treadmill adaptation paradigm, with the faster paced belt moving under the more affected limb. Step length asymmetry (SLA) and phase coordination index (PCI) were the primary outcome measures used to assess spatial and temporal gait symmetries, respectively. It was predicted that participants with a worse baseline symmetry would have a greater response to split-belt treadmill adaptation. Following this adaptation paradigm, PwMS experienced aftereffects that improved gait symmetry, with a significant difference between predicted responders and nonresponders in both SLA and PCI change (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.