SynthesisArthritis research & therapy2023
Giant cell arteritis-related cerebrovascular ischemic events: a French retrospective study of 271 patients, systematic review of the literature and meta-analysis.
Synthesis in Arthritis research & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Intracranial GCA: a comprehensive systematic review.Rheumatology (Oxford, England) · 2025Pooled it
- Prognosis and Long-Term Outcome of Stenotic Large Vessel Involvement in Giant Cell Arteritis.Arthritis & rheumatology (Hoboken, N.J.) · 2026Article
- Long-Term Follow-Up in Patients with Large-Vessel Vasculitis Applying Extracranial and Transcranial Duplex Sonography.Diagnostics (Basel, Switzerland) · 2026Article
- Recurrent vertebrobasilar stroke in giant cell arteritis associated with progressive prostate carcinoma: a case report and literature review.Clinical rheumatology · 2026Review
- Phenotypic heterogeneity of giant cell arteritis in an Asian cohort: clinical, imaging, and laboratory characteristics.Frontiers in medicine · 2026Article
- A corona-like distribution and patchy pattern of cerebellar infarcts identify patients with giant cell arteritis.Therapeutic advances in neurological disorders · 2026Article
- Prevalence, characteristics, and outcomes of patients with low baseline C-reactive protein in giant cell arteritis.Arthritis research & therapy · 2025Observational
- Risk Factors and Pharmacological Interventions Impacting Cerebrovascular Ischemic Events in Giant Cell Arteritis: A Narrative Review.Immunity, inflammation and disease · 2025Review
- Polymyalgia rheumatica and giant cell arteritis following COVID-19 vaccination: Results from a nationwide survey.Human vaccines & immunotherapeutics · 2024Article
- [Necrosis of the tongue as a clinical manifestation of giant cell arteritis].Innere Medizin (Heidelberg, Germany) · 2024Article
- Giant-cell arteritis related strokes: scoping review of mechanisms and rethinking treatment strategy?Frontiers in neurology · 2023Article
- Increased vertebral canal diameter measured by ultrasonography as a sign of vasculitis in patients with giant cell arteritis.Frontiers in medicine · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCerebrovascular ischemic events (CIE) are among the most severe complications of giant cell arteritis (GCA). Heterogeneity between different studies in the definition of GCA-related CIE leads to uncertainty regarding their real prevalence. The aim of our study was to evaluate the prevalence and describe the characteristics of GCA-related CIE in a well-phenotyped cohort completed by a meta-analysis of the existing literature.
methodsIn this retrospective study performed in the Lille University Hospital, all consecutive patients with GCA according to American College of Rheumatology (ACR) diagnostic criteria were included from January 1, 2010, to December 31, 2020. A systematic review of the literature using MEDLINE and EMBASE was performed. Cohort studies of unselected GCA patients reporting CIE were included in the meta-analysis. We calculated the pooled summary estimate of GCA-related CIE prevalence.
resultsA total of 271 GCA patients (89 males, mean age 72 ± 9 years) were included in the study. Among them, 14 (5.2%) presented with GCA-related CIE including 8 in the vertebrobasilar territory, 5 in the carotid territory, and 1 patient having multifocal ischemic and hemorrhagic strokes related to intra-cranial vasculitis. Fourteen studies were included in the meta-analysis, representing a total population of 3553 patients. The pooled prevalence of GCA-related CIE was 4% (95% CI 3-6, I
conclusionsThe pooled prevalence of GCA-related CIE was 4%. Our cohort identified an association between GCA-related CIE, lower BMI, and vertebral, intracranial, and axillary arteries involvement on various imaging modalities.
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