ArticleJournal of neuroengineering and rehabilitation2023
Change in activity patterns in the prefrontal cortex in different phases during the dual-task walking in older adults.
Article in Journal of neuroengineering and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- The relationship between motor and cognitive performance and cortical activity in patients with multiple sclerosis: a systematic review of functional near-infrared spectroscopy studies.Frontiers in rehabilitation sciences · 2026Pooled it
- Advances in gait research related to Alzheimer's disease.Frontiers in neurology · 2025Pooled it
- Cognitive-motor dual-task training on gait and balance in stroke patients: meta-analytic report and trial sequential analysis of randomized clinical trials.Journal of neuroengineering and rehabilitation · 2024Pooled it
- Additional Effects of 1-Hz rTMS Combined With Tai Chi Chuan on Dual-Task Performance Among Older Adults With Sleep Disorders and MCI: An fNIRS-Based Randomized Controlled Trial.Brain and behavior · 2026Trial
- Repetitive transcranial magnetic stimulation influences cognitive-motor dual-task performance in children with cerebral palsy: a randomized controlled study.Journal of neuroengineering and rehabilitation · 2025Trial
- Enhancing cognitive and physical performance in older adults through wearable sensor-based interactive cognitive-motor training: a randomized clinical trial.Scientific reports · 2025Trial
- The choice stepping reaction task: how prefrontal network topology reconfigures in aging and dementia.GeroScience · 2026Article
- Cognitive Impairment Alters Cortical Adaptation and Gait Regulation During Obstacle Walking in Patients With Parkinson's Disease: Evidence From Temporal fNIRS and Gait Dynamics.Journal of movement disorders · 2026Article
- The Effects of Different Attentional Focus During Walking on Prefrontal Cortical Activation in Young Healthy Adults.The European journal of neuroscience · 2026Article
- How aging impacts cortical dynamics and gait during dual-task turning revealed by fNIRS.GeroScience · 2026Article
- Gender- and domain-specific effects of a 6-month multidimensional exercise program on attention and verbal fluency in physically inactive older adults.Frontiers in aging · 2026Article
- Dual-task standing in older adults with mild cognitive impairment: postural control complexity, prefrontal activation, and cognitive task performance.Frontiers in neuroscience · 2026Article
- Decreased brain activity within the dorsolateral prefrontal cortex in adolescents during cognitive control tasks: a functional near-infrared spectroscopy study.Neurophotonics · 2026Article
- Disability Moderates Dual Task Walking Performance and Neural Efficiency in Older Adults With Multiple Sclerosis.Neurorehabilitation and neural repair · 2024Article
- Effects of Cognitive-Motor and Motor-Motor Dual Tasks on Gait Performance in Older Adults with Sarcopenia.Healthcare (Basel, Switzerland) · 2024Article
- Review of the Brain's Behaviour after Injury and Disease for Its Application in an Agent-Based Model (ABM).Biomimetics (Basel, Switzerland) · 2024Review
- Frontal and parietal cortices activation during walking is repeatable in older adults based on fNIRS.Heliyon · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies using functional near-infrared spectroscopy (fNIRS) have shown that dual-task walking leads to greater prefrontal cortex (PFC) activation compared to the single-task walking task. However, evidence on age-related changes in PFC activity patterns is inconsistent. Therefore, this study aimed to explore the changes in the activation patterns of PFC subregions in different activation phases (early and late phases) during both single-task and dual-task walking in both older and younger adults.
methodsOverall, 20 older and 15 younger adults performed a walking task with and without a cognitive task. The activity of the PFC subregions in different phases (early and late phases) and task performance (gait and cognitive task) were evaluated using fNIRS and a gait analyzer.
resultsThe gait (slower speed and lower cadence) and cognitive performance (lower total response, correct response and accuracy rate, and higher error rate) of older adults was poorer during the dual task than that of younger adults. Right dorsolateral PFC activity in the early period in older adults was higher than that in younger adults, which declined precipitously during the late period. Conversely, the activity level of the right orbitofrontal cortex in the dual-task for older adults was lower than for younger adults.
conclusionsThese altered PFC subregion-specific activation patterns in older adults would indicate a decline in dual-task performance with aging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.