Evidence map›Paper›PMID 37420203›Full record

SynthesisBMC urology2023

A systematic review and meta-analysis of outcomes between dusting and fragmentation in retrograde intrarenal surgery.

Zhi Wen, Li Wang, Yang Liu, Jing Huang, Cai-Xia Chen, Chong-Jian Wang, Lin-Lin Chen, Xue-Song Yang

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07639385 (Fragmentation Vs Dusting Using TFL With FANS for Renal Stones Less Than 2cm), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07639385 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Fragmentation Vs Dusting Using TFL With FANS for Renal Stones Less Than 2cm

TypeinterventionalSponsorBir HospitalRan2026 to 2027Enrolled86ConditionsThulium Fiber Laser, Fans, Lithotripsy, Laser, Renal StoneArmsDusting, Fragmentation
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhi Wen *Department of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Li Wang *Department of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Yang Liu *Department of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Jing HuangDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Cai-Xia ChenDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Chong-Jian WangDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Lin-Lin ChenDepartment of Hemodialysis, Sixth People's Hospital of Nanchong, Nanchong, Sichuan Province, China.
Xue-Song YangDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China. Xuesongyang2022@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesComparing stone-free rates and associated outcome measures between two surgical modalities of lithotripsy fragmentation and removal or spontaneous passage of dust during retrograde intrarenal surgery (RIRS).

methodsIn March 2023, we conducted a literature search in several widely used databases worldwide, including PubMed, Embase, and Google Scholar. We only considered English articles and excluded pediatric patients. Reviews and protocols without any published data were excluded. We also excluded articles with conference abstracts and irrelevant content. We used the Cochran-Mantel-Haenszel method and random-effects models to assess inverse variances and 95% confidence intervals (CIs) for mean differences in categorical variables. The results were reported as odds ratios (ORs) and 95% CIs. Statistical significance was set at p < 0.05.

resultsOur final meta-analysis included nine articles, comprising two randomized controlled trials (RCTs) and seven cohort studies. The total number of patients included in these studies was 1326, and all studies used holmium laser lithotripsy. The pooled analysis of the dust and fragmentation groups showed that the fragmentation group had a higher stone-free rate (OR 0.6; 95% CI 0.41 - 0.89; p = 0.01); the dust group had a shorter operative time (WMD - 11.6 min; 95% CI - 19.56 - -3.63; p = 0.004); and the dust group had a higher retreatment rate (OR 2.03; 95% CI 1.31 - 3.13; p = 0.001). There was no statistically significant difference between the two groups in terms of length of hospital stay, overall complications, or postoperative fever.

conclusionsOur results showed that both procedures could be safely and effectively used for upper ureteral and renal calculi lithotripsy, the dust group had potential advantages over the fragmentation group in terms of the operation time, and the fragmentation group had certain advantages in terms of stone-free rate and retreatment rate.

Indexed as

Kidney CalculiLithotripsyLithotripsy, LaserNephrolithotomy, PercutaneousHumansKidneyTreatment OutcomeCalculi3Lithotripsy 4Nephrectomy2Surgery5Ureteroscopy1

Identifiers

PMID37420203
PMCPMC10329318

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.