Evidence map›Paper›PMID 37420132›Full record

ArticleInternational journal of colorectal disease2023

Predictors of outcome for treatment of enterovaginal fistula : Therapeutical strategies for treatment.

Moritz Drefs, Sebastian Schömer Cuenca, Ulrich Wirth, Florian Kühn, Maria Burian, Jens Werner, Petra Zimmermann

Open access · hybridAbstract read
In one paragraph

Article in International journal of colorectal disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Moritz DrefsDepartment of General, Visceral and Transplant Surgery, University Hospital of Munich, Munich 81377, Germany.
Sebastian Schömer CuencaKlinikum Freising, Freising, Germany.
Ulrich WirthDepartment of General, Visceral and Transplant Surgery, University Hospital of Munich, Munich 81377, Germany.
Florian KühnDepartment of General, Visceral and Transplant Surgery, University Hospital of Munich, Munich 81377, Germany.
Maria BurianDepartment of General, Visceral and Transplant Surgery, University Hospital of Munich, Munich 81377, Germany.
Jens WernerDepartment of General, Visceral and Transplant Surgery, University Hospital of Munich, Munich 81377, Germany.
Petra ZimmermannDepartment of General, Visceral and Transplant Surgery, University Hospital of Munich, Munich 81377, Germany. petra.zimmermann@med.uni-muenchen.de.
München Klinik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnterovaginal fistulas represent a serious complication of various diseases and therapeutic procedures, often associated with complicated clinical courses and massive impairment of quality of life. As underlying conditions and procedures are multifarious, therapeutic approaches are challenging and have to be tailored individually. As the therapeutic management is complex and individualized, multiple surgical interventions might be necessary.

methodsThe aim of this study was to identify possible predictors for outcome in the treatment enterovaginal fistula patients. The study was realized as a retrospective analysis. Ninety-two patients treated with enterovaginal fistulas between 2004 and 2016 were analyzed. Patient characteristics, therapeutic data, and endoscopic findings were stratified according to etiology, closure rate and time, as well as recurrence of fistula. Main outcome measure was the overall rate of fistula closure.

resultsOverall therapeutic success rate was 67.4%. Postoperatively derived fistulas were most frequent (40.2%), mainly after rectal surgery (59.5%). Postoperative and non-IBD-inflammation associated fistulas had better outcome than IBD-, radiotherapy-, and tumor-related fistulas (p = 0.001). Successful fistula closure was observed more frequently after radical surgical interventions, best results observed after transabdominal surgery (p < 0.001). Fistula recurrence was also less frequently observed after radical surgical therapies (p = 0.029). A temporary stoma was associated with higher incidence of fistula closure (p = 0.013) and lower incidence of fistula recurrence (p = 0.042) in the postoperative subgroup, as well as shortened therapy period in all groups (p = 0.031).

conclusionEnterovaginal fistulas are a result of various etiologies, and treatment should be adjusted accordingly. A very sustainable, rapid, and persistent therapeutic success can be expected after radical surgical approaches with temporary diverting stoma. This is especially true for postoperatively derived fistulas.

Indexed as

Rectal FistulaRectovaginal FistulaFemaleHumansQuality of LifeRetrospective StudiesTreatment OutcomeEnterovaginal fistulasRectovaginal fistulasTherapeutic outcome for enterovaginal fistulas

Identifiers

PMID37420132
PMCPMC10329052
OpenAlexW4383499029

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.