Trial reportInternational journal of obesity (2005)2023
Associations of obesity phenotypes with weight change, cardiometabolic benefits, and type 2 diabetes incidence during a lifestyle intervention: results from the PREVIEW study.
Trial report in International journal of obesity (2005), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
20 authors at 13 institutions in 10 countries.
Ruixin ZhuDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Maija Huttunen-LenzInstitute for Nursing Science, University of Education Schwäbisch Gmünd, Schwäbisch Gmünd, Germany.ORCID 0000-0002-1034-1613
Gareth StrattonApplied Sports, Technology, Exercise and Medicine (A-STEM) Research Centre, Swansea University, Swansea, UK.ORCID 0000-0001-5618-0803
Teodora Handjieva-DarlenskaDepartment of Pharmacology and Toxicology, Medical University of Sofia, Sofia, Bulgaria.
Svetoslav HandjievDepartment of Pharmacology and Toxicology, Medical University of Sofia, Sofia, Bulgaria.
Jouko SundvallFinnish Institute for Health and Welfare, Helsinki, Finland.
Marta P SilvestreHuman Nutrition Unit, School of Biological Sciences, Department of Medicine, University of Auckland, Auckland, New Zealand.
Elli JaloDepartment of Food and Nutrition, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-9987-1716
Kirsi H PietiläinenObesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-8522-1288
Tanja C AdamDepartment of Nutrition and Movement Sciences, NUTRIM, School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0002-7840-5003
Mathijs DrummenDepartment of Nutrition and Movement Sciences, NUTRIM, School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.
Elizabeth J SimpsonMRC/ARUK Centre for Musculoskeletal Ageing Research, ARUK Centre for Sport, Exercise and Osteoarthritis, National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham, UK.ORCID 0000-0001-9353-6258
Moira A TaylorMRC/ARUK Centre for Musculoskeletal Ageing Research, ARUK Centre for Sport, Exercise and Osteoarthritis, National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham, UK.ORCID 0000-0003-4100-8343
Sally D PoppittHuman Nutrition Unit, School of Biological Sciences, Department of Medicine, University of Auckland, Auckland, New Zealand.ORCID 0000-0002-2214-8378
Santiago Navas-CarreteroCentre for Nutrition Research, University of Navarra, Pamplona, Spain.ORCID 0000-0002-5163-2230
J Alfredo MartinezCentro de Investigacion Biomedica en Red Area de Fisiologia de la Obesidad y la Nutricion (CIBEROBN), Madrid, Spain.
Wolfgang SchlichtDepartment of Exercise and Health Sciences, University of Stuttgart, Stuttgart, Germany.ORCID 0000-0002-2134-2259
Mikael FogelholmDepartment of Food and Nutrition, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-8110-102X
Jennie Brand-MillerSchool of Life and Environmental Sciences and Charles Perkins Centre, the University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-6797-8754
Anne RabenDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark. ara@nexs.ku.dk.ORCID 0000-0001-5229-4491
University of Helsinki · FIMaastricht University · NLMedical University of Sofia · BGNational Institute for Health Research · GBUniversity of Auckland · NZUniversity of Copenhagen · DKFinnish Institute for Health and Welfare · FIMadrid Institute for Advanced Studies · ESNavarre Institute of Health Research · ESSwansea University · GBThe University of Sydney · AUUniversity of Design Schwäbisch Gmünd · DEUniversity of Stuttgart · DE
Funding
Biotechnology and Biological Sciences Research CouncilDepartment of Health
6 · The paper itself
Abstract
BACKGROUND/
objectivesSome individuals with overweight/obesity may be relatively metabolically healthy (MHO) and have a lower risk of cardiovascular disease than those with metabolically unhealthy overweight/obesity (MUO). We aimed to compare changes in body weight and cardiometabolic risk factors and type 2 diabetes incidence during a lifestyle intervention between individuals with MHO vs MUO.
methodsThis post-hoc analysis included 1012 participants with MHO and 1153 participants with MUO at baseline in the randomized trial PREVIEW. Participants underwent an eight-week low-energy diet phase followed by a 148-week lifestyle-based weight-maintenance intervention. Adjusted linear mixed models and Cox proportional hazards regression models were used.
resultsThere were no statistically significant differences in weight loss (%) between participants with MHO vs MUO over 156 weeks. At the end of the study, weight loss was 2.7% (95% CI, 1.7%-3.6%) in participants with MHO and 3.0% (2.1%-4.0%) in those with MUO. After the low-energy diet phase, participants with MHO had smaller decreases in triglyceride (mean difference between MHO vs MUO 0.08 mmol·L
conclusionsIndividuals with MUO had greater improvements in some cardiometabolic risk factors during the low-energy diet phase, but had smaller improvements during long-term lifestyle intervention than those with MHO.
Indexed as
Cardiovascular DiseasesDiabetes Mellitus, Type 2Metabolic SyndromeBody Mass IndexGlucoseHumansIncidenceObesityOverweightPhenotypeRisk FactorsTriglyceridesGlucoseTriglycerides
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Associations of obesity phenotypes with weight change, cardiometabolic benefits, and type 2 diabetes incidence during a lifestyle intervention: results from the PREVIEW study. · full record | OpenQuestion