ArticleAIDS and behavior2023
Psychosocial Syndemic Classes and Longitudinal Transition Patterns Among Sexual Minority men Living with or Without HIV in the Multicenter AIDS Cohort Study (MACS).
Article in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Associations between cannabis use, cannabis use motivations and past year polysubstance use among people living with HIV in Florida.AIDS care · 2026Article
- Discrimination, relationship quality, and the mental health of sexual minority men in relationships: A test of the psychological mediation hypothesis.Psychology of sexual orientation and gender diversity · 2026Article
- Latent health behavior classes and associations with depressive symptoms and metabolic syndrome among women with and without HIV in the MACS/WIHS Combined Cohort Study.Journal of health psychology · 2026Article
- Syndemic Psychosocial Conditions among Youth Living with HIV: a Latent Class Analysis.AIDS and behavior · 2024Article
- Longitudinal Analysis of Overlapping Psychosocial Factors Predicting Incident Hospitalization Among Mixed HIV Serostatus Men who have Sex with Men in the Multicenter AIDS Cohort Study.AIDS and behavior · 2024Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
Mental health and substance use epidemics interact to create psychosocial syndemics, accelerating poor health outcomes. Using latent class and latent transition analyses, we identified psychosocial syndemic phenotypes and their longitudinal transition pathways among sexual minority men (SMM) in the Multicenter AIDS Cohort Study (MACS, n = 3,384, mean age 44, 29% non-Hispanic Black, 51% with HIV). Self-reported depressive symptoms and substance use indices (i.e., smoking, hazardous drinking, marijuana, stimulant, and popper use) at the index visit, 3-year and 6-year follow-up were used to model psychosocial syndemics. Four latent classes were identified: "poly-behavioral" (19.4%), "smoking and depression" (21.7%), "illicit drug use" (13.8%), and "no conditions" (45.1%). Across all classes, over 80% of SMM remained in that same class over the follow-ups. SMM who experienced certain psychosocial clusters (e.g., illicit drug use) were less likely to transition to a less complex class. These people could benefit from targeted public health intervention and greater access to treatment resources.
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