Evidence map›Paper›PMID 37417951›Full record

ArticleThe Journal of experimental medicine2023

Lymph node metastasis: An immunological burden.

Amanda W Lund

Abstract readComment
In one paragraph

Article in The Journal of experimental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Integrins as Key Mediators of Metastasis.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Targeting FAPActa pharmaceutica Sinica. B · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Amanda W LundRonald O. Perelman Department of Dermatology, Department of Pathology, NYU Grossman School of Medicine, Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.ORCID 0000-0001-7389-9983

Funding

Project 4P50CA225450 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KIRCHHOFF, TOMAS · 2019 to 2025
$12.5M
Project 3: The Evolving Role of Regional Lymph Nodes in Melanoma ProgressionU54CA263001 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Eva Hernando, Iman Osman · 2022 to 2026
$11.6M
Investigating T Cell Egress via Lymphatic Vessels in MelanomaR01CA238163 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LUND, AMANDA W. · 2019 to 2023
$1.9M
Cancer Research InstituteNCI NIH HHS P50 CA225450NCI NIH HHS R01 CA238163NCI NIH HHS U54 CA263001NIH HHS R01CA238163
6 · The paper itself

Abstract

Lymph node metastasis in breast cancer depends in part on the acquisition of an IFN-dependent, MHC-II+ state that induces regulatory T cell expansion and local immune suppression (Lei et al. 2023. J. Exp. Med.https://doi.org/10.1084/jem.20221847).

Indexed as

Breast NeoplasmsLymphatic MetastasisHumansT-Lymphocytes, Regulatory

Identifiers

PMID37417951
PMCPMC10327691

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.