Evidence map›Paper›PMID 37417238›Full record

ReviewStroke2023

Management of Stroke in Patients With Chronic Liver Disease: A Practical Review.

Neal S Parikh, Elora Basu, Mu Ji Hwang, Russel Rosenblatt, Lisa B VanWagner, Hana I Lim, Santosh B Murthy, Hooman Kamel

Abstract readReview
In one paragraph

Review in Stroke, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Neal S ParikhClinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology (N.S.P., E.B., S.B.M., H.K.), Weill Cornell Medicine, New York, NY.
Elora Basu
Mu Ji HwangDepartment of Neurology, Brown University, Providence, RI (M.J.H.).
Russel RosenblattDivision of Gastroenterology and Hepatology, Department of Internal Medicine (R.R.), Weill Cornell Medicine, New York, NY.
Lisa B VanWagnerDivision of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern, Dallas (L.B.V.).ORCID 0000-0002-6264-2573
Hana I LimDivision of Hematology and Oncology, Department of Internal Medicine.(H.I.L.), Weill Cornell Medicine, New York, NY.ORCID 0000-0003-4465-9619
Santosh B MurthyClinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology (N.S.P., E.B., S.B.M., H.K.), Weill Cornell Medicine, New York, NY.ORCID 0000-0002-4950-0992
Hooman KamelClinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology (N.S.P., E.B., S.B.M., H.K.), Weill Cornell Medicine, New York, NY.ORCID 0000-0002-5745-0307

Funding

AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenicstroke (ARCADIA)U01NS095869 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRODERICK, JOSEPH PAUL, KAMEL, HOOMAN · 2017 to 2022
$22.0M
Blood pressure as a modifiable risk factor for cardiovascular events in liver transplant recipientsR56HL155093 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI VANWAGNER, LISA B · 2021 to 2021
$774k
Role of Liver Fibrosis in Cognitive Impairment and DementiaK23AG073524 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI PARIKH, NEAL S · 2021 to 2023
$585k
NHLBI NIH HHS R56 HL155093NIA NIH HHS K23 AG073524NINDS NIH HHS U01 NS095869
6 · The paper itself

Abstract

Chronic liver disease (CLD) is a highly prevalent condition. There is burgeoning recognition that there are many people with subclinical liver disease that may nonetheless be clinically significant. CLD has a variety of systemic aberrations relevant to stroke, including thrombocytopenia, coagulopathy, elevated liver enzymes, and altered drug metabolism. There is a growing body of literature on the intersection of CLD and stroke. Despite this, there have been few efforts to synthesize these data, and stroke guidelines provide scant guidance on this topic. To fill this gap, this multidisciplinary review provides a contemporary overview of CLD for the vascular neurologist while appraising data regarding the impact of CLD on stroke risk, mechanisms, and outcomes. Finally, the review addresses acute and chronic treatment considerations for patients with stroke-ischemic and hemorrhagic-and CLD.

Indexed as

Blood Coagulation DisordersLiver DiseasesStrokeThrombocytopeniaChronic DiseaseHemorrhageHumanscerebrovascular disordersliver diseasesstroke

Identifiers

PMID37417238
PMCPMC10527812

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.