Evidence map›Paper›PMID 37417205›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2023

Epstein-Barr virus genotype-1 and Mediterranean + strain in gastric cancer biopsies of Ghanaian patients.

Jeffery Ampofo-Asiedu, Emmanuel Ayitey Tagoe, Darkwah Owusua Afua Abrahams, Bernard Petershie, Osbourne Quaye

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jeffery Ampofo-AsieduWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra 00233, Ghana.ORCID 0000-0002-4343-3645
Emmanuel Ayitey TagoeDepartment of Medical Laboratory Sciences, University of Ghana, Accra 00233, Ghana.ORCID 0000-0001-7179-1872
Darkwah Owusua Afua AbrahamsDepartment of Pathology, University of Ghana Medical School, University of Ghana and Korle-Bu Teaching Hospital, Accra 00233, Ghana.
Bernard PetershieDepartment of Pathology, University of Ghana Medical School, University of Ghana and Korle-Bu Teaching Hospital, Accra 00233, Ghana.
Osbourne QuayeWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra 00233, Ghana.ORCID 0000-0002-0621-876X
University of Ghana · GH

Funding

Wellcome TrustWellcome Trust DEL-15-007
6 · The paper itself

Abstract

Gastric cancer (GC) prevalence is on the increase in Ghana, and Epstein-Barr virus (EBV) is one of the factors that have been implicated in the etiology of the cancer. It is therefore important to know the contribution of EBV genotype and strains that are associated with GC. In this study, we aimed at genotyping EBV and determining predominant strains in GC biopsies in Ghanaian patients. Genomic DNA was extracted from 55 GC biopsies (cases) and 63 normal gastric tissues (controls) were amplified by polymerase chain reaction (PCR) using specific primers for EBV detection and genotyping followed by PCR fragments sequencing. Epstein-Barr virus positivity were 67.3% and 49.2% in the GC and normal biopsies, respectively. Both cases and controls had the Mediterranean + strain of EBV. The predominant genotype of the virus in the GC cases was genotype-1 (75.7%) compared to 66.7% of genotype-2 among the control group. Infection was associated with GC in the study population (OR = 2.11,

Indexed as

Epstein-Barr Virus InfectionsStomach NeoplasmsBiopsyGenotypeGhanaHerpesvirus 4, HumanHumansEBV epidemiologyEpstein-Barr virusgastric cancergenotypingGhanaian patientsMediterranean +

Identifiers

PMID37417205
PMCPMC10621474
OpenAlexW4383483109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.