Evidence map›Paper›PMID 37417136›Full record

ArticleIndian journal of ophthalmology2023

Knowledge and perception of health-care professionals on clinical trials in India: A pan-Indian cross-sectional survey.

Gopal S Pillai, C S Sheeba, Manabjyoti Barman, Alok Sen, Natarajan Sundaram, Merin Dickson, Shamilin Joyal, Manjisa Choudhury, Merlin Mery Joy, K G Deepthi and 2 more

Abstract read
In one paragraph

Article in Indian journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gopal S PillaiHead of Department of Ophthalmology and Chief of Vitreo-Retinal Services, Amrita Institute of Medical Sciences (AIMS), Kochi, Kerala, India.
C S SheebaDirector and Head of Department of Opthalmology, Regional Institute of Ophthalmology, RIO Thiruvanthapuram, Kerala, India.
Manabjyoti BarmanHead of Department of Vitreo-Retina, Sri Sankaradeva Nethralaya, Guwahati, Assam, India.
Alok SenHead of Department of Vitreo-Retina and Uvea, Shri Sadguru Netra Chikitsalaya (SNC), Chitrakoot, Madhya Pradesh, India.
Natarajan SundaramChief of Vitreo-Retinal Services Department, Aditya Jyot Eye Hospital Pvt. Ltd. (AJEH), Mumbai, Maharashtra, India.
Merin DicksonIOCTNBIRAC Project, AIMS, Kochi, Kerala, India.
Shamilin JoyalIOCTNBIRAC Project, AIMS, Kochi, Kerala, India.
Manjisa ChoudhuryIOCTN-BIRAC Project, Sri Sankaradeva Nethralaya, Guwahati, Assam, India.
Merlin Mery JoyIOCTNBIRAC Project, AIMS, Kochi, Kerala, India.
K G DeepthiIOCTN-BIRAC Project, RIO Thiruvanthapuram, Kerala, India.
Poonam JangidIOCTN-BIRAC Project, SNC, Chitrakoot, Madhya Pradesh, India.
Shruti DudwadkarIOCTN-BIRAC Project, AJEH, Mumbai, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose of the study was to evaluate the knowledge and perception of health-care professionals (HCPs), such as doctors/surgeons, pharmacists, nurses, optometrists, and lab technicians, on clinical trials (CTs) in India. Methods: The study was a pan-Indian cross-sectional survey initiated by the Indian Ophthalmology Clinical Trial Network (IOCTN) by using a previously validated questionnaire for three months of data collection. An online survey was used to record information regarding demographics, CT knowledge, and CT perception among HCPs. Results: A total of 630 responses were recorded from HCPs: 207 doctors and surgeons, 159 pharmacists, and 264 laboratory technicians, nurses, and optometrists across India. Over 90% of HCPs had a clear knowledge on the purpose of CTs, the informed consent (IC) process, ethical approval by the Drugs Controller General of India (DCGI). About 80% and 90% were aware of confidentiality of patients, voluntariness of participation, and good clinical practice. Surprisingly, less than 50% had lesser knowledge regarding monetary incentives of CT participants (CTPs). A slightly positive perception was observed regarding the potential benefits of CTPs, compensation related to injury, and importance of obtaining IC. Less than 50% had a negative perception that monetary compensation to CTPs led to bias and deprivation of standard treatments. However, no significant difference was observed between other aspects of demographics and perception regarding CTs. Conclusion: We observed doctors and surgeons to be having the highest regarding CTs, followed by pharmacists. The survey highlighted the necessity of scheduling awareness programs among the HCPs, which would improve their misconceptions and perception of CTs while interacting with patients for CT enrollment.

Indexed as

Health Knowledge, Attitudes, PracticeSurgeonsCross-Sectional StudiesHumansIndiaPerceptionSurveys and QuestionnairesClinical trialhealth-care professionalsknowledgemulti-centricpan-Indianperception

Identifiers

PMID37417136
PMCPMC10491074

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.