Trial reportAnnals of African medicine
Effectiveness of three mouth rinsing agents against mutans
Trial report in Annals of African medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Green synthesis of TiO₂ nanoparticles using cyanobacterial phycobiliproteins for antibacterial and antioxidant toothpaste applications.BMC microbiology · 2026Article
- The role of probiotics in modulating cariogenic bacteria and oral health outcomes: A systematic review and risk of bias assessment.The Saudi dental journal · 2025Review
- Molecular and Microbial Detections of Streptococcus mutans and Lactobacilli in Dental Caries: An Experimental Study on Iranian Children Aged 5-9.Clinical and experimental dental research · 2024Article
- Antimicrobial Efficacy of Chemomechanical Carie Removal Agents-A Systematic Integrative Review.Biomedicines · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dental caries is one of the most common chronic childhood diseases and is a cause of continuous discomfort through impaired function and esthetics. To control dental caries, the removal of plaque is of utmost importance, and that further necessitates the use of chemotherapeutic agents. Several side effects associated with chlorhexidine have stimulated the search for an alternative chemotherapeutic agent. Aims: This study aims to compare the effectiveness of probiotic mouth rinse with kidodent mouth rinse, and placebo against mutans Streptococcus and Lactobacillus acidophilus (LA). Materials and Methods: The present study was a randomized parallel double-blinded clinical study which included 90 children of ages 6-15 years who were randomly allocated into three groups: Group 1 - placebo (n = 30), Group 2 - kidodent (n = 30), and Group 3 - probiotic (n = 30). Stimulated salivary samples were collected from all the children after rinsing with distilled water (first reading), and after rinsing with respective mouthwash (placebo/kidodent/probiotic mouth rinse) of their groups during the first visit (second readings). Samples were collected again after using mouth rinse for 14 days (third readings) and used for detection of pH, and levels of Streptococcus mutans (SM) and LA counts. Data were subjected to statistical analysis. Results: Statistically significant difference was seen between placebo versus kidodent, placebo versus probiotic but there was no statistically significant difference between kidodent versus probiotic after the immediate rinse and post 15 days of rinse. Conclusion: Kidodent and probiotic mouth rinse are more efficacious and have equivalent efficacy in reducing SM and LA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.