Evidence map›Paper›PMID 37416811›Full record

ArticleNeurosurgical focus: Video2023

Management protocol and surgical techniques for MRI-Negative Cushing's disease: a series of 6 cases.

Nidhisha Sadhwani, Ashish Suri, Amol Raheja, Santanu Kumar Bora, Rajesh Khadgawat, Mehar Chand Sharma, Ajay Garg, Rajni Sharma

Open access · diamondAbstract read
In one paragraph

Article in Neurosurgical focus: Video, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Nidhisha SadhwaniDepartments of Neurosurgery.
Ashish SuriDepartments of Neurosurgery.
Amol RahejaDepartments of Neurosurgery.
Santanu Kumar BoraDepartments of Neurosurgery.
Rajesh KhadgawatEndocrinology.
Mehar Chand SharmaNeuropathology.
Ajay GargNeuroradiology, and.
Rajni SharmaPaediatric Endocrinology, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · INEndocrinology Research Center · RUHeliophysics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Up to 40% of Cushing's disease (CD) patients show no evidence of an adenoma on dynamic contrast-enhanced MRI. Inferior petrosal sinus sampling (IPSS) remains the gold standard for diagnosis in these patients. Remission rates in MRI-Negative CD are far less at 50%-71%, compared with patients in whom an adenoma is identified on MRI. Endoscopic endonasal transsphenoidal surgery is the surgical approach of choice in these cases. Various adjuncts can be used to localize an adenoma. In this video, the authors highlight their additional usage of pituitary perfusion MRI for identification of the adenoma. They present their stepwise management algorithm and surgical techniques for sellar and suprasellar exploration in 6 cases of MRI-Negative CD operated on by the senior author (A.S.). The video can be found here: https://stream.cadmore.media/r10.3171/2023.4.FOCVID2318.

Indexed as

Cushing’s diseaseendoscopic transsphenoidal surgeryMRI negativepituitary explorationpituitary perfusionpituitary surgery

Identifiers

PMID37416811
PMCPMC10321547
OpenAlexW4382797795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.