Evidence map›Paper›PMID 37416757›Full record

ArticleOpen forum infectious diseases2023

An NDM-Producing

Patricia J Simner, Yehudit Bergman, Rick Conzemius, Emily Jacobs, Tsigereda Tekle, Stephan Beisken, Pranita D Tamma

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
5.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Review
  3. Optimizing target inactivation to treat multidrug-resistantAntimicrobial agents and chemotherapy · 2026
    Article
  4. ComparativeAntimicrobial agents and chemotherapy · 2026
    Article
  5. Article
  6. Aztreonam plus ceftazidime/avibactam broth disk elution test: failure to detect Escherichia coli with PBP-3 insertions.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  7. Sulbactam-Durlobactam for Carbapenem-ResistantPathogens (Basel, Switzerland) · 2026
    Review
  8. HighMicrobiology spectrum · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Antimicrobial agents and chemotherapy · 2025
    Article
  17. Article
  18. Article
  19. New Perspectives on Antimicrobial Agents: Sulbactam-durlobactam.Antimicrobial agents and chemotherapy · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Patricia J SimnerDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yehudit BergmanDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Rick ConzemiusAres Genetics, Vienna, Austria.
Emily JacobsDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Tsigereda TekleDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Stephan BeiskenAres Genetics, Vienna, Austria.
Pranita D TammaDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-4143-6324
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cefiderocol and ceftazidime-avibactam plus aztreonam (CZA-ATM) are preferred treatment regimens for New Delhi metallo-β-lactamase (NDM)-producing infections. Methods: We report the case of a US patient who traveled to India to receive a renal transplant. He subsequently experienced pyelonephritis by an NDM-producing Results: An Conclusions: This is the first clinical case of a US patient harboring an NDM-producing isolate exhibiting resistance to all available β-lactam agents. The isolate's unexpected resistance to cefiderocol and CZA-ATM was likely due to a combination of (1) a modified PBP3 (increased MICs to both regimens), (2) truncated iron-binding protein (increased cefiderocol MIC), and (3) a

Indexed as

antimicrobial resistanceaztreonamcefiderocolceftazidime-avibactamPBP3

Identifiers

PMID37416757
PMCPMC10319620
OpenAlexW4377041737

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.