Evidence map›Paper›PMID 37416742›Full record

ReviewAnnals of gastroenterological surgery2023

Locoregional treatment for colorectal liver metastases aiming for precision medicine.

Harufumi Maki, Anish J Jain, Antony Haddad, Mateo Lendoire, Yun Shin Chun, Jean-Nicolas Vauthey

Open access · goldAbstract readReview
In one paragraph

Review in Annals of gastroenterological surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  8. Cancers · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Harufumi MakiDepartment of Surgical Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA.ORCID https://orcid.org/0000-0002-9032-1371
Anish J JainDepartment of Surgical Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA.ORCID https://orcid.org/0000-0001-8695-3969
Antony HaddadDepartment of Surgical Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA.ORCID https://orcid.org/0000-0002-3422-3718
Mateo LendoireDepartment of Surgical Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA.ORCID https://orcid.org/0000-0002-7796-3644
Yun Shin ChunDepartment of Surgical Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA.ORCID https://orcid.org/0000-0003-1384-8927
Jean-Nicolas VautheyDepartment of Surgical Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA.ORCID https://orcid.org/0000-0003-4921-5427
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
TRAINING OF ACADEMIC SURGICAL ONCOLOGISTST32CA009599 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Ashley M Holder, Jennifer A. Wargo · 1988 to 2026
$13.2M
NCI NIH HHS P30 CA016672NCI NIH HHS T32 CA009599
6 · The paper itself

Abstract

In patients with colorectal liver metastases (CLM), surgery is potentially curative. The use of novel surgical techniques and complementary percutaneous ablation allows for curative-intent treatment even in marginally resectable cases. Resection is used as part of a multidisciplinary approach, which for nearly all patients will include perioperative chemotherapy. Small CLM can be treated with parenchymal-sparing hepatectomy (PSH) and/or ablation. For small CLM, PSH results in better survival and higher rates of resectability of recurrent CLM than non-PSH. For patients with extensive bilateral distribution of CLM, two-stage hepatectomy or fast-track two-stage hepatectomy is effective. Our increasing knowledge of genetic alterations allows us to use them as prognostic factors alongside traditional risk factors (e.g. tumor diameter and tumor number) to select patients with CLM for resection and guide surveillance after resection. Alteration in RAS family genes (hereafter referred to as "

Indexed as

ablation techniquescirculating tumor DNAcolorectal neoplasmshepatectomyliver neoplasmsmutationneoplasm metastasis

Identifiers

PMID37416742
PMCPMC10319606
OpenAlexW4377139293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.