Evidence map›Paper›PMID 37416733›Full record

ArticleAnnals of gastroenterological surgery2023

Prognostic significance of osteosarcopenia in older adults with colorectal cancer.

Yasuhiro Takano, Keita Kodera, Shu Tsukihara, Sumika Takahashi, Yasunobu Kobayashi, Muneyuki Koyama, Hironori Kanno, Satoshi Ishiyama, Nobuyoshi Hanyu, Ken Eto

Open access · goldAbstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yasuhiro TakanoDepartment of Surgery Tokyo Generel Hospital Tokyo Japan.ORCID https://orcid.org/0000-0001-7474-3833
Keita KoderaDepartment of Surgery Kasai Shoikai Hospital Tokyo Japan.
Shu TsukiharaDepartment of Surgery Tokyo Generel Hospital Tokyo Japan.
Sumika TakahashiDepartment of Surgery Tokyo Generel Hospital Tokyo Japan.
Yasunobu KobayashiDepartment of Surgery Tokyo Generel Hospital Tokyo Japan.
Muneyuki KoyamaDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.
Hironori KannoDepartment of Surgery Tokyo Generel Hospital Tokyo Japan.
Satoshi IshiyamaDepartment of Surgery Kasai Shoikai Hospital Tokyo Japan.
Nobuyoshi HanyuDepartment of Surgery Tokyo Generel Hospital Tokyo Japan.
Ken EtoDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.
University of Tokyo Hospital · JPJikei University School of Medicine · JPKansai Rosai Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Osteopenia and sarcopenia, features of the aging process, are recognized as major health problems in an aging society. This study investigated the prognostic impact of osteosarcopenia, the coexistence of osteopenia and sarcopenia, in older adults undergoing curative resection for colorectal cancer. Methods: We retrospectively reviewed data of older adults aged 65-98 y who had undergone curative resection for colorectal cancer. Osteopenia was evaluated by bone mineral density measurement in the midvertebral core of the 11th thoracic vertebra on preoperative computed tomography images. Sarcopenia was evaluated by measuring the skeletal muscle cross-sectional area at the third lumbar vertebra level. Osteosarcopenia was defined as the coexistence of osteopenia and sarcopenia. We explored the relationship of preoperative osteosarcopenia with the disease-free and overall survival after curative resection. Results: Among the 325 patients included, those with osteosarcopenia had significantly lower overall survival rates than those with osteopenia or sarcopenia alone ( Conclusion: Osteosarcopenia was a strong predictor of poor outcomes in older adults undergoing curative resection for colorectal cancer, suggesting an important role of osteosarcopenia in an aging society.

Indexed as

colorectal cancerolder adultsosteopeniaosteosarcopeniasarcopenia

Identifiers

PMID37416733
PMCPMC10319614
OpenAlexW4321370337

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.