Evidence map›Paper›PMID 37416731›Full record

ArticleAnnals of gastroenterological surgery2023

Long-term risk of a fatty liver in liver donors.

Ryoichi Goto, Norio Kawamura, Masaaki Watanabe, Yoshikazu Ganchiku, Akihisa Nagatsu, Kazufumi Okada, Yoichi M Ito, Toshiya Kamiyama, Tsuyoshi Shimamura, Akinobu Taketomi

Open access · goldAbstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Long-term risk of a fatty liver in liver donors.Annals of gastroenterological surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ryoichi GotoDepartment of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan.ORCID https://orcid.org/0000-0002-8237-0034
Norio KawamuraDepartment of Transplant Surgery Hokkaido University Graduate School of Medicine Sapporo Japan.
Masaaki WatanabeDepartment of Transplant Surgery Hokkaido University Graduate School of Medicine Sapporo Japan.
Yoshikazu GanchikuDepartment of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan.
Akihisa NagatsuDepartment of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan.
Kazufumi OkadaData Science Center, Promotion Unit, Institute of Health Science Innovation for Medical Care Hokkaido University Hospital Sapporo Japan.
Yoichi M ItoData Science Center, Promotion Unit, Institute of Health Science Innovation for Medical Care Hokkaido University Hospital Sapporo Japan.
Toshiya KamiyamaDepartment of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan.
Tsuyoshi ShimamuraDivision of Organ Transplantation Hokkaido University Hospital Sapporo Japan.
Akinobu TaketomiDepartment of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan.
Hokkaido University · JPHokkaido University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Approximately 30 years have passed since the first experience of living donor liver transplantation. The time to evaluate the long-term safety of living donors has been fulfilled. Meanwhile, nonalcoholic fatty liver disease is increasingly common and a critical problem. The aim of this study was to evaluate the safety of living donor, focusing on fatty liver postdonation hepatectomy. Methods: Living donors ( Results: Among 212 living liver donors, 30 (14.2%) detected fatty liver at 5.3 ± 4.2 years postdonation. The cumulative incidence rates of fatty liver were 3.1%, 12.1%, 22.1%, and 27.7% at 2, 5, 10, and 15 years postdonation, respectively. Of 30 subjects who developed fatty liver, 18 (60%) displayed a severe steatosis (L/S ratio <0.9). Five (16.7%) had a prior history of excessive alcohol abuse. More than 30% developed metabolic syndrome including obesity, hyperlipidemia, and diabetes. Although six (20%) had a Fib-4 index of >1.3, which included a case with a Fib-4 index of >2.67, no significant increased Fib-4 index was observed in the subjects with fatty liver as compared to those without fatty liver ( Conclusion: Living donors with risk factors for developing fatty liver should be carefully followed-up for the prevention and management of metabolic syndrome.

Indexed as

body mass indexliver transplantationliving donorpediatrics

Identifiers

PMID37416731
PMCPMC10319612
OpenAlexW4320491917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.