ArticleiScience2023
High-throughput longitudinal electrophysiology screening of mature chamber-specific hiPSC-CMs using optical mapping.
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Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
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Who cites it
14 citing papers in PubMed, 15 citations in OpenAlex.
- Do Stimulants Promote Arrhythmic Risk: Insights From a Human-Induced Pluripotent Stem Cell-Derived Cardiomyocyte Model.Journal of arrhythmia · 2026Article
- Reconstructing AF-associated atrial fibrosis: Patient-specific iPSC models, fit-for-purpose atrial microphysiological systems, and nanomedicine.Materials today. Bio · 2026Review
- A new approach methodology for studying intrinsic ventricular arrhythmias in Fabry disease.Frontiers in cardiovascular medicine · 2026Article
- Engineered heart tissues formed with cardiac progenitors and differentiated cardiomyocytes exhibit similar physiologic properties at differentiation-matched timepoints.Biofabrication · 2025Article
- AI-guided laser purification of human iPSC-derived cardiomyocytes for next-generation cardiac cell manufacturing.Communications biology · 2025Article
- 3D Spatiotemporal Activation Mapping of Cardiac Organoids Using Conformal Shell Microelectrode Arrays (MEAs).Research square · 2025Article
- Ion channel traffic jams: the significance of trafficking deficiency in long QT syndrome.Cell discovery · 2025Review
- Developing an approach for evaluating the cardiotoxic potential of botanicals.Frontiers in toxicology · 2025Review
- Metabolic changes of human induced pluripotent stem cell-derived cardiomyocytes and teratomas after transplantation.iScience · 2024Article
- Microphysiological systems to advance human pathophysiology and translational medicine.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Review
- Bipolar Patient-Specific In Vitro Diagnostic Test Reveals Underlying Cardiac Arrhythmia Phenotype Caused by Calcium Channel Genetic Risk Factor.Biological psychiatry global open science · 2024Article
- OptoDyCE-plate as an affordable high throughput imager for all optical cardiac electrophysiology.Journal of molecular and cellular cardiology plus · 2023Article
- OptoDyCE-plate as an affordable high throughput imager for all optical cardiac electrophysiology.bioRxiv : the preprint server for biology · 2023Article
- Optical Mapping of Cardiomyocytes in Monolayer Derived from Induced Pluripotent Stem Cells.Cells · 2023Review
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 2 countries.
Andrew AllanCairn Research, Graveney Road, Faversham, Kent ME13 8UP UK.
Jeffery CreechUniversity of Michigan, Frankel Cardiovascular Regeneration Core Laboratory, Ann Arbor, MI 48109, USA.
Christian HausnerUniversity of Michigan, Frankel Cardiovascular Regeneration Core Laboratory, Ann Arbor, MI 48109, USA.
Peyton KrajcarskiUniversity of Michigan, Frankel Cardiovascular Regeneration Core Laboratory, Ann Arbor, MI 48109, USA.
Bianca GunawanUniversity of Michigan, Frankel Cardiovascular Regeneration Core Laboratory, Ann Arbor, MI 48109, USA.
Noah PoulinUniversity of Michigan, Frankel Cardiovascular Regeneration Core Laboratory, Ann Arbor, MI 48109, USA.
Paul KozlowskiMichigan Medicine, Internal Medicine-Cardiology, Ann Arbor, MI 48109, USA.
Christopher Wayne ClarkUniversity of Michigan, School of Public Health, Department of Environmental Health Sciences, Ann Arbor, MI 48109, USA.
Rachel DowUniversity of Michigan, Frankel Cardiovascular Regeneration Core Laboratory, Ann Arbor, MI 48109, USA.
Prakaimuk SaraithongUniversity of Michigan, Frankel Cardiovascular Regeneration Core Laboratory, Ann Arbor, MI 48109, USA.
Devin B MairDepartment of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Travis BlockStemBioSys, Inc, 3463 Magic Drive, Suite 110, San Antonio, TX 78229, USA.
Andre Monteiro da RochaUniversity of Michigan, Frankel Cardiovascular Regeneration Core Laboratory, Ann Arbor, MI 48109, USA.
Deok-Ho KimDepartment of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Todd J HerronUniversity of Michigan, Frankel Cardiovascular Regeneration Core Laboratory, Ann Arbor, MI 48109, USA.
University of Michigan · USJohns Hopkins University · USCairn Research (United Kingdom) · GBMichigan Medicine · US
Funding
Microphysiological Model of Human Cardiac Sympathetic InnervationR01HL164936 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KIM, DEOK-HO, KWON, CHULAN · 2022 to 2025
$3.2MHit-to-lead optimization for heart failure drug discoveryR01HL148068 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ESPINOZA-FONSECA, LENNANE MICHEL, HERRON, TODD JOSEPH · 2019 to 2022
$2.9MEngineering Clinical Trials on a Chip for Dystrophin-Deficient Muscular DystrophyUH3TR003271 · NCATS · JOHNS HOPKINS UNIVERSITY · PI KASS, DAVID ALAN, KIM, DEOK-HO · 2022 to 2024
$2.4MTranscriptomic Entropy to Quantify Maturation of PSC-Derived CardiomyocytesR01HL156947 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KIM, DEOK-HO, KWON, CHULAN · 2021 to 2024
$2.3MDISEASE MODELING AND PHENOTYPIC DRUG SCREENING FOR DYSTROPHIC CARDIOMYOPATHYR01HL146436 · NHLBI · UNIVERSITY OF WASHINGTON · PI KIM, DEOK-HO · 2019 to 2022
$2.2MhiPSC Cardiomyocyte HTS Electrophysiology System for Detecting Drug Induced Fatal Cardiac ArrhythmiasR44ES027703 · NIEHS · CARTOX, LLC · PI HERRON, TODD JOSEPH · 2019 to 2020
$1.3MNCATS NIH HHS UH3 TR003271NHLBI NIH HHS R01 HL146436NHLBI NIH HHS R01 HL148068NHLBI NIH HHS R01 HL156947NHLBI NIH HHS R01 HL164936NIEHS NIH HHS R44 ES027703
Abstract
hiPSC-CMs are being considered by the Food and Drug Administration and other regulatory agencies for
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Cell biologyMedicineScreening in health technology
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.