Evidence map›Paper›PMID 37415926›Full record

ReviewFrontiers in systems neuroscience2023

Neurocognitive and cerebellar function in ADHD, autism and spinocerebellar ataxia.

Maurizio Cundari, Susanna Vestberg, Peik Gustafsson, Sorina Gorcenco, Anders Rasmussen

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in systems neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
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  13. Alcohol Toxicity in the Developing Cerebellum.Diagnostics (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maurizio CundariDepartment of Experimental Medical Science, Faculty of Medicine, Lund University, Lund, Sweden.
Susanna VestbergDepartment of Psychology, Faculty of Social Science, Lund University, Lund, Sweden.
Peik GustafssonChild and Adolescent Psychiatry, Department of Clinical Sciences Lund, Medical Faculty, Lund University, Lund, Sweden.
Sorina GorcencoDepartment for Clinical Sciences Lund, Neurology, Lund University, Skåne University Hospital, Lund, Sweden.
Anders RasmussenDepartment of Experimental Medical Science, Faculty of Medicine, Lund University, Lund, Sweden.
Lund University · SEHelsingborgs lasarett · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cerebellum plays a major role in balance, motor control and sensorimotor integration, but also in cognition, language, and emotional regulation. Several neuropsychiatric disorders such as attention deficit-hyperactivity disorder (ADHD), autism spectrum disorder (ASD), as well as neurological diseases such as spinocerebellar ataxia type 3 (SCA3) are associated with differences in cerebellar function. Morphological abnormalities in different cerebellar subregions produce distinct behavioral symptoms related to the functional disruption of specific cerebro-cerebellar circuits. The specific contribution of the cerebellum to typical development may therefore involve the optimization of the structure and function of cerebro-cerebellar circuits underlying skill acquisition in multiple domains. Here, we review cerebellar structural and functional differences between healthy and patients with ADHD, ASD, and SCA3, and explore how disruption of cerebellar networks affects the neurocognitive functions in these conditions. We discuss how cerebellar computations contribute to performance on cognitive and motor tasks and how cerebellar signals are interfaced with signals from other brain regions during normal and dysfunctional behavior. We conclude that the cerebellum plays a role in many cognitive functions. Still, more clinical studies with the support of neuroimaging are needed to clarify the cerebellum's role in normal and dysfunctional behavior and cognitive functioning.

Indexed as

attention deficit hyperactivity disorder (ADHD)autism spectrum disorder (ASD)cerebellumcognitionneurologyneuropsychiatryneuropsychologyspinocerebellar ataxia (SCA)

Identifiers

PMID37415926
PMCPMC10321758
OpenAlexW4381662846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.