Evidence map›Paper›PMID 37415837›Full record

ArticleExperimental and therapeutic medicine2023

Glucocorticoids ameliorate cardiorenal syndrome through the NPR1/SGK1 pathway in natriuretic peptide receptor A‑heterozygous mice.

Yao-Meng Huang, Tong-Xin Li, Shu-Yu Li, Xiao-Ran Zhu, Ying Li, Dang-Yang Liu, Wei-Min Li, Lin-Quan Yang, Kun-Shen Liu, Chao Liu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yao-Meng HuangThe First Cardiology Division, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050030, P.R. China.
Tong-Xin LiThe First Cardiology Division, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050030, P.R. China.
Shu-Yu LiThe First Cardiology Division, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050030, P.R. China.
Xiao-Ran ZhuThe First Cardiology Division, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050030, P.R. China.
Ying LiThe First Cardiology Division, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050030, P.R. China.
Dang-Yang LiuThe First Cardiology Division, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050030, P.R. China.
Wei-Min LiThe First Cardiology Division, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050030, P.R. China.
Lin-Quan YangDepartment of Pharmacy, Hebei General Hospital, Shijiazhuang, Hebei 050057, P.R. China.
Kun-Shen LiuThe First Cardiology Division, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050030, P.R. China.
Chao LiuThe First Cardiology Division, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050030, P.R. China.
Hebei Medical University · CNFirst Affiliated Hospital of Hebei Medical University · CNHebei General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natriuretic peptides, which are produced by the heart, bind to natriuretic peptide receptor A (NPR1 encoded by natriuretic peptide receptor 1 gene) and cause vasodilation and natriuresis. Thus, they serve an important role in regulating blood pressure. In the present study, microinjection of CRISPR associated protein 9/single guide RNA into fertilized C57BL/6N mouse eggs was performed to generate filial generation zero (F0) Npr1 knockout homozygous mice (Npr1

Indexed as

cardiorenal syndromeglucocorticoidnatriuretic peptide receptor Aserum/glucocorticoid regulated kinase 1

Identifiers

PMID37415837
PMCPMC10320660
OpenAlexW4381684645

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.