Evidence map›Paper›PMID 37415827›Full record

ReviewFrontiers in cellular and infection microbiology2023

Mechanisms of lung damage in tuberculosis: implications for chronic obstructive pulmonary disease.

Alex Kayongo, Brian Nyiro, Trishul Siddharthan, Bruce Kirenga, William Checkley, Moses Lutaakome Joloba, Jerrold Ellner, Padmini Salgame

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  3. Mechanisms ofBreathe (Sheffield, England) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Alex KayongoDepartment of Medicine, Center for Emerging Pathogens, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Brian NyiroDepartment of Medicine, Center for Emerging Pathogens, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Trishul SiddharthanDivision of Pulmonary and Critical Care Medicine, University of Miami, Miami, FL, United States.
Bruce KirengaMakerere University College of Health Sciences, Lung Institute, Makerere University, Kampala, Uganda.
William CheckleyDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, United States.
Moses Lutaakome JolobaMakerere University College of Health Sciences, Lung Institute, Makerere University, Kampala, Uganda.
Jerrold EllnerDepartment of Medicine, Center for Emerging Pathogens, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Padmini SalgameDepartment of Medicine, Center for Emerging Pathogens, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Rutgers, The State University of New Jersey · USMakerere University · UGJohns Hopkins University · USUniversity of Miami · US

Funding

Training of Ugandans in Basic Research on TB and Emerging Infectious DiseasesD43TW009093 · FIC · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI ELLNER, JERROLD J. · 2014 to 2023
$2.2M
Investigating the role of altered lung microbiome in fueling Th17 mediated airway inflammation in COPD among HIV-infected individualR21TW012354 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KAYONGO, ALEX · 2022 to 2023
$573k
FIC NIH HHS D43 TW009093FIC NIH HHS R21 TW012354
6 · The paper itself

Abstract

Pulmonary tuberculosis is increasingly recognized as a risk factor for COPD. Severe lung function impairment has been reported in post-TB patients. Despite increasing evidence to support the association between TB and COPD, only a few studies describe the immunological basis of COPD among TB patients following successful treatment completion. In this review, we draw on well-elaborated

Indexed as

Mycobacterium tuberculosisPulmonary Disease, Chronic ObstructiveTuberculosisTuberculosis, PulmonaryHumansLungadaptive immunityCOPD - chronic obstructive pulmonary diseasehost-directed therapy (HDT)innate immunityTuberculosis

Identifiers

PMID37415827
PMCPMC10320222
OpenAlexW4381665549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.