Evidence map›Paper›PMID 37415805›Full record

ArticlePulmonary circulation2023

Balloon pulmonary angioplasty outcomes in patients previously treated by pulmonary endarterectomy surgery are inferior to those of inoperable patients.

Louise C Kirkby, Matthew S Rodgers, Liliana Amaral-Almeida, Karen Sheares, Mark Toshner, Katherine Bunclark, Aleksandra Bartnik, Dolores Taboada, Choo Ng, Fouad J Taghavi and 7 more

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Chronic thromboembolic pulmonary disease.The European respiratory journal · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Louise C KirkbyDepartment of Medicine University of Cambridge Cambridge UK.ORCID 0000-0002-2329-8319
Matthew S RodgersDepartment of Medicine University of Cambridge Cambridge UK.ORCID 0000-0001-9485-2869
Liliana Amaral-AlmeidaPulmonary Vascular Disease Unit Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
Karen ShearesPulmonary Vascular Disease Unit Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
Mark ToshnerDepartment of Medicine University of Cambridge Cambridge UK.
Katherine BunclarkPulmonary Vascular Disease Unit Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
Aleksandra BartnikDepartment of Medicine University of Cambridge Cambridge UK.
Dolores TaboadaPulmonary Vascular Disease Unit Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
Choo NgDepartment of Cardiothoracic Surgery Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
Fouad J TaghaviDepartment of Cardiothoracic Surgery Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
Steven TsuiDepartment of Cardiothoracic Surgery Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
John E CannonPulmonary Vascular Disease Unit Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
Jonathan R Weir-McCallDepartment of Medicine University of Cambridge Cambridge UK.
John G CoghlanDepartment of Interventional Cardiology Royal Free Hospital NHS Foundation Trust London UK.
David P JenkinsDepartment of Cardiothoracic Surgery Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
Joanna Pepke-ZabaPulmonary Vascular Disease Unit Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
Stephen P HooleDepartment of Interventional Cardiology Royal Papworth Hospital NHS Foundation Trust Cambridge UK.ORCID 0000-0002-3530-3808
Papworth Hospital NHS Foundation Trust · GBUniversity of Cambridge · GBRoyal Free London NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary endarterectomy (PEA) may not achieve full clearance of vascular obstructions in patients with more distal chronic thromboembolic pulmonary hypertension (CTEPH). Balloon pulmonary angioplasty (BPA) may be indicated to treat these residual vascular lesions. We compared whether patients post-PEA (PP) treated by BPA derived similar benefit to those who had inoperable CTEPH (IC), and assessed predictors of BPA response after surgery. We treated 109 patients with BPA-89 with IC and 20 PP. Serial right heart catheterization performed at baseline (immediately before BPA) and 3 months after completing BPA, compared pulmonary vascular resistance (PVR), mean pulmonary artery pressure (mPAP) as well as change in WHO functional class and 6-minute walk distance. We also assessed the impact of total thrombus tail length (TTTL) from photographed PEA surgical specimens and PP computed tomography pulmonary angiography (CTPA)-quantified residual disease burden on BPA response. PP and IC groups did not differ significantly in terms of demographics, baseline hemodynamics or procedural characteristics. However, IC derived greater hemodynamic benefit from BPA: ΔPVR (-27.9 ± 20.2% vs. -13.9 ± 23.9%,

Indexed as

Balloon pulmonary angioplasty (BPA)Chronic thromboembolic pulmonary hypertension (CTEPH)Mean pulmonary artery pressure (mPAP)Pulmonary endarterectomy (PEA)Pulmonary vascular resistance (PVR)

Identifiers

PMID37415805
PMCPMC10320194
OpenAlexW4383262584

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.