Evidence map›Paper›PMID 37415738›Full record

ArticleOncology research2023

Mutations in epigenetic regulator

Sha Zhu, Nanwei Xu, Jiayu Liang, Fengnian Zhao, Zilin Wang, Yuchao Ni, Jindong Dai, Jinge Zhao, Xingming Zhang, Junru Chen and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Oncology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Focal ablation therapy presents promising results for selectively localized prostate cancer patients.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Sha ZhuDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Nanwei XuDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jiayu LiangDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Fengnian ZhaoDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Zilin WangDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Yuchao NiDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jindong DaiDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jinge ZhaoDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Xingming ZhangDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Junru ChenDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Guangxi SunDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Pengfei ShenDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Hao ZengDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: KMT2 (lysine methyltransferase) family enzymes are epigenetic regulators that activate gene transcription. Methods: We included 221 prostate cancer patients diagnosed between 2014 and 2021 in West China Hospital of Sichuan University with cell-free DNA-based liquid biopsy test results in this study. We investigated the association between Results: The Conclusions:

Indexed as

Prostate-Specific AntigenProstatic Neoplasms, Castration-ResistantDNA-Binding ProteinsEpigenesis, GeneticHumansLiquid BiopsyMaleMutationTreatment OutcomeDNA-Binding ProteinsKMT2C protein, humanProstate-Specific AntigenBiomarkerEpigenetic regulatorKMT2CLiquid biopsyProstate cancerSurvival

Identifiers

PMID37415738
PMCPMC10319590
OpenAlexW4381955827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.