Evidence map›Paper›PMID 37415693›Full record

ArticleFrontiers in psychiatry2023

Association between family functioning and psychotic transition in ultra-high risk adolescents and young adults.

Vladimir Adrien, Justine Liewig, Thomas Diot, Florian Ferreri, Stephane Mouchabac, Caroline Dubertret, Julie Bourgin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Vladimir AdrienAP-HP, Department of Psychiatry, Saint-Antoine Hospital, Sorbonne Université, Paris, France.
Justine LiewigDepartment of Child and Adolescent Psychiatry, Nord-Essonne Hospital, Bures-sur-Yvette, France.
Thomas DiotAP-HP, Department of Psychiatry, Saint-Antoine Hospital, Sorbonne Université, Paris, France.
Florian FerreriAP-HP, Department of Psychiatry, Saint-Antoine Hospital, Sorbonne Université, Paris, France.
Stephane MouchabacAP-HP, Department of Psychiatry, Saint-Antoine Hospital, Sorbonne Université, Paris, France.
Caroline DubertretAP-HP, Department of Psychiatry, Louis Mourier Hospital, Université Paris Cité, Faculté de Médecine, Colombes, France.
Julie BourginDepartment of Child and Adolescent Psychiatry, Nord-Essonne Hospital, Bures-sur-Yvette, France.
Centre Hospitalier Sud-Essonne Dourdan-Etampes · FRCentre National de la Recherche Scientifique · FRAssistance Publique – Hôpitaux de Paris · FRInserm · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Psychotic transition (PT) is a crucial stage in schizophrenia. The Comprehensive Assessment of At-Risk Mental States (CAARMS) scale can be used to identify individuals at ultra-high risk (UHR) for psychosis and to evaluate their risk of PT. Many environmental and genetic factors have been identified as contributing to the development and decompensation of schizophrenia. This study aimed to determine if the quality of family functioning is associated with PT risk in UHR individuals aged between 11 and 25 years after 1 year of follow-up. Methods: From January to November 2017, 45 patients aged 12 to 25 consulting for psychiatric reasons were included. Twenty-six were classified as UHR of PT at the CAARMS. Family functioning was assessed by the Family Assessment Device-Global Functioning (FAD-GF). Thirty-seven of these patients (30% men, mean age 16 ± 2.5) were reassessed at 8-14 months of recruitment. Survival analysis was used to examine the impact of family functioning on PT risk. Results: A total of 40% of UHR patients were classified as psychotic at reassessment. Survival analysis showed that better family functioning is a significant protective factor for PT in this population. Discussion: This result suggests that the global family functioning has an impact at 1 year on the risk of PT in the population of adolescents and young adults who consult the hospital for psychiatric reasons. A family intervention may be effective in reducing PT risk in this population and should be considered as a potential therapeutic option.

Indexed as

adolescentenvironmentFAD-60family functioningpsychotic transition

Identifiers

PMID37415693
PMCPMC10320389
OpenAlexW4381661523

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.