Evidence map›Paper›PMID 37415621›Full record

ReviewKidney medicine2023

Iron-Deficiency Anemia in CKD: A Narrative Review for the Kidney Care Team.

Debra Hain, Donna Bednarski, Molly Cahill, Amy Dix, Bryce Foote, Mary S Haras, Rory Pace, Orlando M Gutiérrez

Open access · goldAbstract readReview
In one paragraph

Review in Kidney medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Effect of pharmacist interventions in chronic kidney disease: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Debra HainFlorida Atlantic University, Boca Raton, FL.
Donna BednarskiDetroit Medical Center Harper University Hospital, Detroit, MI.
Molly CahillKansas City Kidney Consultants, Kansas City, MO.
Amy DixAkebia Therapeutics Inc, Cambridge, MA.
Bryce FooteAkebia Therapeutics Inc, Cambridge, MA.
Mary S HarasGeorgetown University School of Nursing, Washington, DC.
Rory PaceSatellite Healthcare, San Jose, CA.
Orlando M GutiérrezUniversity of Alabama at Birmingham, Birmingham, AL.
Akebia Therapeutics (United States) · USDetroit Medical Center · USFlorida Atlantic University · USGeorgetown University · USKidney Associates · USSatellite Healthcare (United States) · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anemia is a common complication of chronic kidney disease (CKD) and is associated with increased mortality and reduced health-related quality of life. Anemia is characterized by a decrease in hemoglobin, the iron-rich protein that the body uses for oxygen transport. Iron is required to produce hemoglobin, and disruptions in the iron homeostasis can lead to iron-deficiency anemia. Management of anemia in individuals with CKD is typically performed by a team of physicians, nurse practitioners, physician assistants, or registered nurses. Throughout the care continuum, the management can be enhanced by multidisciplinary care, and individuals with CKD can benefit from the involvement of other specialties, with dietitians/nutritionists playing an important role. However, a key area of unmet clinical need is how to assess and address iron-deficiency anemia. This review aims to provide an overview of iron-deficiency anemia in CKD and how this may be diagnosed and managed by the entire kidney care team, such as describing the mechanisms underlying iron homeostasis, the complications of iron-deficiency anemia, and the current challenges associated with its diagnosis and treatment in CKD. Opportunities for each multidisciplinary team member to add value to the care of individuals with CKD and iron-deficiency anemia are also described.

Indexed as

Anemiachronic kidney diseasehemoglobiniron deficiencyiron-deficiency anemiairon metabolism

Identifiers

PMID37415621
PMCPMC10319843
OpenAlexW4378189628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.