Evidence map›Paper›PMID 37415105›Full record

ReviewBMC infectious diseases2023

Intramedullary disseminated sporotrichosis in an immunocompetent patient: case report and review of the literature.

Jennifer L Perrault, Levi A Endelman, Mark R Kraemer, Derrick Chen, Wendell B Lake, M Shahriar Salamat

Open access · goldAbstract readReviewCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jennifer L PerraultUniversity of Pikeville Kentucky College of Osteopathic Medicine, 147 Sycamore Street, Pikeville, KY, 41501, USA.
Levi A EndelmanDepartment of Pathology and Laboratory Medicine, University of Wisconsin, 600 Highland Avenue, Madison, WI, 53792, USA.
Mark R KraemerDepartment of Neurological Surgery, University of Wisconsin, 600 Highland Avenue, Madison, WI, 53792, USA.
Derrick ChenDepartment of Pathology and Laboratory Medicine, University of Wisconsin, 600 Highland Avenue, Madison, WI, 53792, USA.
Wendell B LakeDepartment of Neurological Surgery, University of Wisconsin, 600 Highland Avenue, Madison, WI, 53792, USA.
M Shahriar SalamatDepartment of Pathology and Laboratory Medicine, University of Wisconsin, 600 Highland Avenue, Madison, WI, 53792, USA. ssalamat@wisc.edu.
Highland Community College - Illinois · USNeurological Surgery · USUniversity of Pikeville · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDisseminated sporotrichosis is a severe opportunistic infection that often affects immunocompromised patients after a cutaneous inoculation. Here we present a rare case of disseminated sporotrichosis discovered as a solitary intramedullary thoracic spinal cord lesion in an immunocompetent patient. CASE DESCRIPTION: A 37-year-old man presented with progressive lower limb weakness and sensory changes over 1 week. A spinal magnetic resonance imaging (MRI) revealed a contrast-enhancing intramedullary lesion centered at T10. The patient was afebrile and reported no history of trauma or cutaneous lesions. The lesion was unresponsive to a trial of corticosteroids. A thoracic laminectomy was performed and a biopsy obtained. A cutaneous lesion on the arm was concurrently discovered, which was also biopsied. Both the skin and spinal cord biopsies showed Sporothrix schenckii by macroscopic and microscopic morphology which were later confirmed by MALDI-TOF mass spectrometry.

conclusionThis is a rare case of intramedullary disseminated sporotrichosis affecting the central nervous system of an immunocompetent patient. This unusual presentation should be taken into consideration when such intramedullary lesions are encountered.

Indexed as

SporothrixSporotrichosisAdultAntifungal AgentsBiopsyHumansMaleSkinAntifungal AgentsCase reportCentral nervous systemDisseminated sporotrichosisFungal infectionIntramedullary

Identifiers

PMID37415105
PMCPMC10324153
OpenAlexW4383342985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.