ArticleIntensive care medicine experimental2023
The metabolic cost of inspiratory muscle training in mechanically ventilated patients in critical care.
Article in Intensive care medicine experimental, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- Efficacy of inspiratory muscle training on weaning success in mechanically ventilated ICU patients: a systematic review and network meta-analysis of randomized controlled trials.BMC pulmonary medicine · 2026Pooled it
- Low-Medium and High-Intensity Inspiratory Muscle Training in Critically Ill Patients: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Defining a diaphragm-focused and patient-acceptable inspiratory muscle training (IMT) load in difficult to wean, mechanically ventilated patients: a protocol for a prospective, mixed methods study.BMJ open respiratory research · 2026Article
- Inspiratory muscle training in the healthy adult: The relationship between load, perception, and oxygen consumption.Clinical physiology and functional imaging · 2026Article
- Respiratory Muscle Training in Mechanically Ventilated Adult Patients: Toward a Precise Prescription Based on Current Evidence: A Scoping Review.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiaphragmatic dysfunction is well documented in patients receiving mechanical ventilation. Inspiratory muscle training (IMT) has been used to facilitate weaning by strengthening the inspiratory muscles, yet the optimal approach remains uncertain. Whilst some data on the metabolic response to whole body exercise in critical care exist, the metabolic response to IMT in critical care is yet to be investigated. This study aimed to quantify the metabolic response to IMT in critical care and its relationship to physiological variables.
methodsWe conducted a prospective observational study on mechanically ventilated patients ventilated for ≥ 72 h and able to participate in IMT in a medical, surgical, and cardiothoracic intensive care unit. 76 measurements were taken on 26 patients performing IMT using an inspiratory threshold loading device at 4 cmH
resultsFirst session mean (SD) VO
conclusionsIMT causes a significant load-dependent increase in VO TAKE HOME MESSAGE: The optimal approach to IMT in ICU is uncertain; we measured VO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.