Evidence map›Paper›PMID 37414985›Full record

ReviewInflammation research : official journal of the European Histamine Research Society ... [et al.]2023

The potential roles of Th17 cells in the pathogenesis of oral lichen planus.

Shima Afzali, Elham Mohammadisoleimani, Yaser Mansoori, Poopak Mohaghegh, Maryam Bahmanyar, Behnam Mansoori, Babak Pezeshki, Ghasem Nikfar, Alireza Tavassoli, Abbas Shahi and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. [Research Progress of Peripheral Immune Tolerance in Oral Diseases].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  6. Review
  7. Immune checkpoint inhibitor associated lichenoid eruptions: a review of non-steroidal systemic maintenance therapies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Lack of oral involvement in a large cohort of women with vulvar lichen sclerosus - a multicenter prospective study.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2024
    Observational
  12. Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Shima AfzaliDepartment of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Elham MohammadisoleimaniNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Yaser MansooriNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Poopak MohagheghPediatrics Department, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Maryam BahmanyarPediatrics Department, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Behnam MansooriNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Babak PezeshkiNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Ghasem NikfarNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Alireza TavassoliDepartment of Pathology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Abbas ShahiDepartment of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Abbas.Shahi2012@yahoo.com.
Ali MoravejNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran. A.moravej@fums.ac.ir.
Fasa University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral lichen planus (OLP) is a T cell-mediated chronic autoimmune disease, whose pathogenesis and etiology are not entirely understood. OLP is characterized by subepithelial lymphocyte infiltration and elevated intra-epithelial lymphocytes. The majority of lamina propria lymphocytes are CD4

methodsTo make up this review, studies covering the role of TH17 in different types of lichen planus were selected from major databases.

resultsAs we review in this article, Th17 cells and their signature cytokines play an important role in OLP pathogenesis. As well, utilizing some anti-IL-17 antibodies showed promising results in improving the disease; however, more studies are still needed to better understand and treat OLP.

Indexed as

Intraepithelial LymphocytesLichen Planus, OralChronic DiseaseCytokinesHumansTh17 CellsTh2 CellsCytokinesIL-17IL-22Lichen planusOLPOral Lichen planusTh17

Identifiers

PMID37414985
OpenAlexW4383371940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.