Evidence map›Paper›PMID 37414702›Full record

ArticleEuropean urology2023

Diagnostic Performance and Safety of Positron Emission Tomography with

Devaki Shilpa Surasi, Matthias Eiber, Tobias Maurer, Mark A Preston, Brian T Helfand, David Josephson, Ashutosh K Tewari, Diederik M Somford, Soroush Rais-Bahrami, Bridget F Koontz and 6 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. An intra-patient contemporaneous comparison ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Trial
  4. The German Cancer Consortium (DKTK) multi-center prospective phase 1/2European journal of nuclear medicine and molecular imaging · 2026
    Trial
  5. Imaging Efficacy of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Trial
  6. Interreader and Intrareader Reproducibility ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Trial
  7. Review
  8. A Pilot Study ofThe Prostate · 2026
    Article
  9. Optimization of Administered Activity forWorld journal of nuclear medicine · 2026
    Article
  10. Article
  11. Bladder activity of different PSMA PET radioligands and impact of furosemide.American journal of nuclear medicine and molecular imaging · 2026
    Article
  12. Challenges and Opportunities in Radioligand Therapy.Journal of nuclear medicine technology · 2025
    Review
  13. Observational
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Towards Dual-Tracer SPECT for Prostate Cancer Imaging Using [Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Devaki Shilpa SurasiDepartment of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: dssurasi@mdanderson.org.
Matthias EiberDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Tobias MaurerMartini-Klinik, Hamburg, Germany; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Mark A PrestonBrigham and Women's Hospital, Boston, MA, USA.
Brian T HelfandNorthShore University HealthSystem, Evanston, IL, USA.
David JosephsonTower Urology, Los Angeles, CA, USA; Cedars Sinai Medical Center, Los Angeles, CA, USA.
Ashutosh K TewariMount Sinai Hospital, New York, NY, USA.
Diederik M SomfordDepartment of Urology, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands; Prosper Prostate Cancer Clinics, Nijmegen/Eindhoven, The Netherlands.
Soroush Rais-BahramiDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL, USA.
Bridget F KoontzDuke University School of Medicine, Durham, NC, USA.
Peter J BostromTurku University Central Hospital, Turku, Finland; University of Turku, Turku, Finland.
Albert ChauBlue Earth Diagnostics Ltd, Oxford, UK.
Phillip DavisBlue Earth Diagnostics Inc, Monroe Township, NJ, USA.
David M SchusterDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.
Brian F ChapinDepartment of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
LIGHTHOUSE Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiohybrid (rh)

objectiveTo evaluate the diagnostic performance and safety of DESIGN, SETTING, AND

participantsData on OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Patients underwent positron emission tomography/computed tomography (PET/CT) 50-70 min after an injection of 296 MBq RESULTS AND LIMITATIONS: Of 372 patients screened, 352 had evaluable

conclusionsAcross all risk stratifications, PATIENT SUMMARY: In order to select the most appropriate treatment for patients with prostate cancer, it is critical to diagnose the disease burden accurately at initial diagnosis. In this study, we investigated a new diagnostic imaging agent in a large population of men with primary prostate cancer. We found it to have an excellent safety profile and to provide clinically useful information regarding the presence of disease beyond the prostate.

Indexed as

Positron Emission Tomography Computed TomographyProstatic NeoplasmsGallium RadioisotopesHumansMalePositron-Emission TomographyProspective StudiesProstateGallium RadioisotopesPositron emission tomographyProstate-specific membrane antigenProstatic neoplasmsRadiohybrid prostate-specific membrane antigen

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.