Evidence map›Paper›PMID 37414676›Full record

ArticleTrends in genetics : TIG2023

An miRNA with a major impact on stress.

Sarah Cooper Simmons, A J Robison

Open access · bronzeAbstract readComment
In one paragraph

Article in Trends in genetics : TIG, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sarah Cooper SimmonsDepartment of Physiology, Michigan State University, East Lansing, MI 48824, USA.
A J RobisonDepartment of Physiology, Michigan State University, East Lansing, MI 48824, USA. Electronic address: robiso45@msu.edu.
Michigan State University · US

Funding

Projection-specific gene expression in resilience to chronic stressR01MH111604 · NIMH · MICHIGAN STATE UNIVERSITY · PI Michelle Suzanne Mazei-Robison, ALFRED J ROBISON · 2016 to 2026
$4.9M
NIMH NIH HHS R01 MH111604
6 · The paper itself

Abstract

miRNAs regulate mRNAs, including those important for synapse function in the brain. Mucha and colleagues recently identified a novel miRNA-mRNA interaction in the basolateral amygdala that acts as a homeostatic counter to stress-induced anxiety and synaptic changes, suggesting miRNAs as potential avenues for therapeutic intervention in anxiety disorders.

Indexed as

MicroRNAsBrainMicroRNAs

Identifiers

PMID37414676
PMCPMC10526973
OpenAlexW4383106092

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.