Evidence map›Paper›PMID 37414452›Full record

ArticleAJNR. American journal of neuroradiology2023

Deep Learning-Generated Synthetic MR Imaging STIR Spine Images Are Superior in Image Quality and Diagnostically Equivalent to Conventional STIR: A Multicenter, Multireader Trial.

L N Tanenbaum, S C Bash, G Zaharchuk, A Shankaranarayanan, R Chamberlain, M Wintermark, C Beaulieu, M Novick, L Wang

Abstract readMulticenter Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

L N TanenbaumFrom RadNet (L.N.T., S.C.B.), New York, New York nuromri@gmail.com.ORCID 0000-0003-3326-3192
S C BashFrom RadNet (L.N.T., S.C.B.), New York, New York.ORCID 0000-0002-2572-1010
G ZaharchukStanford University Medical Center (G.Z., C.B.), Stanford, California.ORCID 0000-0001-5781-8848
A ShankaranarayananSubtle Medical (A.S., R.C., L.W.), Menlo Park, California.ORCID 0000-0001-9395-8768
R ChamberlainSubtle Medical (A.S., R.C., L.W.), Menlo Park, California.ORCID 0000-0002-2705-1268
M WintermarkMD Anderson Cancer Center (M.W.), University of Texas, Houston, Texas.ORCID 0000-0002-6726-3951
C BeaulieuStanford University Medical Center (G.Z., C.B.), Stanford, California.ORCID 0000-0002-6036-1962
M NovickAll-American Teleradiology (M.N.), Bay Village, Ohio.
L WangSubtle Medical (A.S., R.C., L.W.), Menlo Park, California.ORCID 0000-0002-5382-5431

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeDeep learning image reconstruction allows faster MR imaging acquisitions while matching or exceeding the standard of care and can create synthetic images from existing data sets. This multicenter, multireader spine study evaluated the performance of synthetically created STIR compared with acquired STIR. MATERIALS AND

methodsFrom a multicenter, multiscanner data base of 328 clinical cases, a nonreader neuroradiologist randomly selected 110 spine MR imaging studies in 93 patients (sagittal T1, T2, and STIR) and classified them into 5 categories of disease and healthy. A DICOM-based deep learning application generated a synthetically created STIR series from the sagittal T1 and T2 images. Five radiologists (3 neuroradiologists, 1 musculoskeletal radiologist, and 1 general radiologist) rated the STIR quality and classified disease pathology (study 1,

resultsFor classification, there was a decrease in interreader agreement expected by randomly introducing synthetically created STIR of 3.23%. For trauma, there was an overall increase in interreader agreement by +1.9%. The lower bound of confidence for both exceeded the noninferiority threshold, indicating interchangeability of synthetically created STIR with acquired STIR. Both the Wilcoxon signed-rank and

conclusionsSynthetically created STIR spine MR images were diagnostically interchangeable with acquired STIR, while providing significantly higher image quality, suggesting routine clinical practice potential.

Indexed as

Deep LearningHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingSpine

Identifiers

PMID37414452
PMCPMC10411840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.