Evidence map›Paper›PMID 37414368›Full record

ArticleJournal of biomedical informatics2023

WindowSHAP: An efficient framework for explaining time-series classifiers based on Shapley values.

Amin Nayebi, Sindhu Tipirneni, Chandan K Reddy, Brandon Foreman, Vignesh Subbian

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amin NayebiDepartment of Systems and Industrial Engineering, University of Arizona, AZ, USA. Electronic address: aminnayebi@arizona.edu.
Sindhu TipirneniDepartment of Computer Science, Virginia Tech, VA, USA.
Chandan K ReddyDepartment of Computer Science, Virginia Tech, VA, USA.
Brandon ForemanCollege of Medicine, University of Cincinnati, OH, USA.
Vignesh SubbianDepartment of Systems and Industrial Engineering, University of Arizona, AZ, USA; Department of Biomedical Engineering, University of Arizona, AZ, USA.

Funding

The Impact of Intracranial Pressure on Cortical Functioning and Cognitive Outcome after Traumatic Brain InjuryK23NS101123 · NINDS · UNIVERSITY OF CINCINNATI · PI FOREMAN, BRANDON · 2017 to 2020
$797k
NINDS NIH HHS K23 NS101123
6 · The paper itself

Abstract

Unpacking and comprehending how black-box machine learning algorithms (such as deep learning models) make decisions has been a persistent challenge for researchers and end-users. Explaining time-series predictive models is useful for clinical applications with high stakes to understand the behavior of prediction models, e.g., to determine how different variables and time points influence the clinical outcome. However, existing approaches to explain such models are frequently unique to architectures and data where the features do not have a time-varying component. In this paper, we introduce WindowSHAP, a model-agnostic framework for explaining time-series classifiers using Shapley values. We intend for WindowSHAP to mitigate the computational complexity of calculating Shapley values for long time-series data as well as improve the quality of explanations. WindowSHAP is based on partitioning a sequence into time windows. Under this framework, we present three distinct algorithms of Stationary, Sliding and Dynamic WindowSHAP, each evaluated against baseline approaches, KernelSHAP and TimeSHAP, using perturbation and sequence analyses metrics. We applied our framework to clinical time-series data from both a specialized clinical domain (Traumatic Brain Injury - TBI) as well as a broad clinical domain (critical care medicine). The experimental results demonstrate that, based on the two quantitative metrics, our framework is superior at explaining clinical time-series classifiers, while also reducing the complexity of computations. We show that for time-series data with 120 time steps (hours), merging 10 adjacent time points can reduce the CPU time of WindowSHAP by 80 % compared to KernelSHAP. We also show that our Dynamic WindowSHAP algorithm focuses more on the most important time steps and provides more understandable explanations. As a result, WindowSHAP not only accelerates the calculation of Shapley values for time-series data, but also delivers more understandable explanations with higher quality.

Indexed as

AlgorithmsBrain Injuries, TraumaticBenchmarkingHumansMachine LearningTime FactorsExplainable artificial intelligenceModel interpretationShapley valueTime-series data

Identifiers

PMID37414368
PMCPMC10552726

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.