ArticleThe Journal of nutrition2023
Evaluation of a Rapid Four-Compartment Model and Stand-Alone Methods in Hispanic Adults.
Article in The Journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Anthropometric-based predictive equations developed with multi-component models for estimating body composition in athletes.European journal of applied physiology · 2025Pooled it
- The Validity of Bioelectrical Impedance Analysis Compared to a Four-Compartment Model in Healthy Adults: A Systematic Review.Journal of functional morphology and kinesiology · 2026Review
- A descriptive analysis of sarcopenia markers in young adults with down syndrome.Experimental gerontology · 2025Article
- Exploring Changes in Body Composition Before and After a National Collegiate Athletic Association Division I Football Season of Marching Artists.International journal of exercise science · 2025Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundA rapid 4-compartment (4C) model integrates dual-energy x-ray absorptiometry (DXA) and multi-frequency bioimpedance analysis (MFBIA), which may be useful for clinical and research settings seeking to employ a multi-compartment model.
objectivesThis study aimed to determine the added benefit of a rapid 4C model over stand-alone DXA and MFBIA when estimating body composition.
methodsOne hundred and thirty participants (n = 60 male; n = 70 female) of Hispanic descent were included in the present analysis. A criterion 4C model that employed air displacement plethysmography (body volume), deuterium oxide (total body water), and DXA (bone mineral) was used to measure fat mass (FM), fat-free mass (FFM), and body fat percent (%BF). A rapid 4C model (DXA-derived body volume and bone mineral; MFBIA-derived total body water) and stand-alone DXA (GE Lunar Prodigy) and MFBIA (InBody 570) assessments were compared against the criterion 4C model.
resultsLin's concordance correlation coefficient values were >0.90 for all comparisons. The standard error of the estimates ranged from 1.3 to 2.0 kg, 1.6 to 2.2 kg, and 2.1 to 2.7% for FM, FFM, and %BF, respectively. The 95% limits of agreement ranged from ±3.0 to 4.2 kg, ±3.1 to 4.2 kg, and ±4.9 to 5.2% for FM, FFM, and %BF, respectively.
conclusionsResults revealed that all 3 methods provided acceptable body composition results. The MFBIA device used in the current study may be a more economically friendly option than DXA or when there is a need to minimize radiation exposure. Nonetheless, clinics and laboratories that already have a DXA device in place or that value having the lowest individual error when conducting a test may consider continuing to use the machine. Lastly, a rapid 4C model may be useful for assessing body composition measures observed in the current study and those provided by a multi-compartment model (e.g., protein).
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