Evidence map›Paper›PMID 37414239›Full record

ArticleArchives of physical medicine and rehabilitation2024

A Single Dermatome Clinical Prediction Rule for Independent Walking 1 Year After Spinal Cord Injury.

Andrew C Smith, Christina Draganich, Wesley A Thornton, Jeffrey C Berliner, Peter J Lennarson, Enrico Rejc, Mitch Sevigny, Susan Charlifue, Candace Tefertiller, Kenneth A Weber

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Andrew C SmithDepartment of Physical Medicine and Rehabilitation, University of Colorado School of Medicine, Aurora, CO. Electronic address: andrew.c2.smith@cuanschutz.edu.
Christina DraganichDepartment of Physical Medicine and Rehabilitation, University of Colorado School of Medicine, Aurora, CO; Craig Hospital, Englewood, CO.
Wesley A ThorntonDepartment of Physical Medicine and Rehabilitation, University of Colorado School of Medicine, Aurora, CO.
Jeffrey C BerlinerDepartment of Physical Medicine and Rehabilitation, University of Colorado School of Medicine, Aurora, CO.
Peter J LennarsonDepartment of Neurosurgery, University of Colorado School of Medicine, Aurora, CO.
Enrico RejcDepartment of Neurosurgery, University of Louisville School of Medicine, Louisville, KY; Department of Medicine, University of Udine, Udine, Italy.
Mitch SevignyCraig Hospital, Englewood, CO.
Susan CharlifueCraig Hospital, Englewood, CO.
Candace TefertillerCraig Hospital, Englewood, CO.
Kenneth A WeberDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA.
Craig Hospital · USUniversity of Colorado Denver · USStanford Medicine · USUniversity of Udine · IT

Funding

Neuroimaging-Based Brain and Spinal Cord Biomarkers for Cervical RadiculopathyK23NS104211 · NINDS · STANFORD UNIVERSITY · PI WEBER, KENNETH ARNOLD · 2018 to 2022
$875k
Improving mechanistic understanding of responsiveness to spinal cord stimulation after spinal cord injuryK01HD106928 · NICHD · UNIVERSITY OF COLORADO DENVER · PI SMITH, ANDREW CRAIG · 2022 to 2025
$508k
NICHD NIH HHS K01 HD106928NINDS NIH HHS K23 NS104211NINDS NIH HHS L30 NS108301
6 · The paper itself

Abstract

objectiveTo derive and validate a simple, accurate CPR to predict future independent walking ability after SCI at the bedside that does not rely on motor scores and is predictive for those initially classified in the middle of the SCI severity spectrum.

designRetrospective cohort study. Binary variables were derived, indicating degrees of sensation to evaluate predictive value of pinprick and light touch variables across dermatomes. The optimal single sensory modality and dermatome was used to derive our CPR, which was validated on an independent dataset.

settingAnalysis of SCI Model Systems dataset.

participantsIndividuals with traumatic SCI. The data of 3679 participants (N=3679) were included with 623 participants comprising the derivation dataset and 3056 comprising the validation dataset.

interventionsNot applicable.

main outcome measuresSelf-reported ability to walk both indoors and outdoors.

resultsPinprick testing at S1 over lateral heels, within 31 days of SCI, accurately identified future independent walkers 1 year after SCI. Normal pinprick in both lateral heels provided good prognosis, any pinprick sensation in either lateral heel provided fair prognosis, and no sensation provided poor prognosis. This CPR performed satisfactorily in the middle SCI severity subgroup.

conclusionsIn this large multi-site study, we derived and validated a simple, accurate CPR using only pinprick sensory testing at lateral heels that predicts future independent walking after SCI.

Indexed as

Clinical Decision RulesSpinal Cord InjuriesHumansNeurologic ExaminationRetrospective StudiesWalkingClinical prediction rulePinprickRehabilitationSpinal cord injuryWalking

Identifiers

PMID37414239
PMCPMC10766862
OpenAlexW4383226986

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.