Evidence map›Paper›PMID 37413960›Full record

SynthesisDrug and alcohol dependence2023

Urine drug testing among Medicaid enrollees initiating buprenorphine treatment for opioid use disorder within 9 MODRN states.

Lindsey Hammerslag, Jeffery Talbert, Julie M Donohue, Michael Sharbaugh, Katherine Ahrens, Lindsay Allen, Anna E Austin, Adam J Gordon, Marian Jarlenski, Joo Yeon Kim and 4 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Drug and alcohol dependence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Primary care professionals' perspectives on tailoring buprenorphine training for rural practice.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lindsey HammerslagDivision of Biomedical Informatics, College of Medicine, University of Kentucky, United States. Electronic address: L.hammerslag@uky.edu.
Jeffery TalbertInstitute for Biomedical Informatics, College of Medicine, University of Kentucky, United States.
Julie M DonohueHealth Policy and Management, University of Pittsburgh School of Public Health, United States.
Michael SharbaughDepartment of Health Policy and Management, University of Pittsburgh School of Public Health, United States.
Katherine AhrensUniversity of Southern Maine, Muskie School of Public Service, United States.
Lindsay AllenFeinberg School of Medicine, Northwestern University, United States.
Anna E AustinGillings School of Global Public Health and Injury Prevention Research Center, University of North Carolina at Chapel Hill, United States.
Adam J GordonProgram for Addiction Research, Clinical Care, Knowledge, and Advocacy, Department of Internal Medicine, University of Utah School of Medicine and VA Salt Lake City Health Care System, United States.
Marian JarlenskiDepartment of Health Policy and Management, University of Pittsburgh School of Public Health, United States.
Joo Yeon KimDepartment of Health Policy and Management, University of Pittsburgh School of Public Health, United States.
Shamis MohamoudThe Hilltop Institute, University of Maryland Baltimore County, United States.
Lu TangDepartment of Biostatistics, University of Pittsburgh School of Public Health, United States.
Marguerite BurnsDepartment of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin, United States.
Writing committee for MODRN

Funding

Examining the quality of opioid use disorder treatment in a Medicaid research networkR01DA048029 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DONOHUE, JULIE MARIE · 2019 to 2021
$3.5M
NIDA NIH HHS R01 DA048029
6 · The paper itself

Abstract

backgroundTreatment guidelines recommend regular urine drug testing (UDT) for persons initiating buprenorphine for opioid use disorder (OUD). However, little is known about UDT utilization. We describe state variation in UDT utilization and examine demographic, health, and health care utilization factors associated with UDT in Medicaid.

methodsWe used Medicaid claims and enrollment data from persons initiating buprenorphine treatment for OUD during 2016-2019 in 9 states (DE, KY, MD, ME, MI, NC, PA, WI, WV). The main outcome was at least 1 UDT within 180 days of buprenorphine initiation, the secondary outcome was at least 3. Logistic regression models included demographics, pre-initiation comorbidities, and health service use. State estimates were pooled using meta-analysis.

resultsThe study cohort included 162,437 Medicaid enrollees initiating buprenorphine. The percent receiving ≥1 UDT varied from 62.1% to 89.8% by state. In the pooled analysis, enrollees with pre-initiation UDT had much higher odds of ≥1 UDT after initiation (aOR=3.83, 3.09-4.73); odds were also higher for enrollees with HIV, HCV, and/or HBV infection (aOR=1.25, 1.05-1.48) or who initiated in later years (2018 v 2016: aOR=1.39, 1.03-1.89; 2019 v 2016: aOR=1.67, 1.24-2.25). The odds of having ≥3 UDT were lower with pre-initiation opioid overdose (aOR=0.79, 0.64-0.96) and higher with pre-initiation UDT (aOR=2.63, 2.13-3.25) or OUD care (aOR=1.35, 1.04-1.74). The direction of associations with demographics varied by state.

conclusionsRates of UDT increased over time and there was variability among states in UDT rates and demographic predictors of UDT. Pre-initiation conditions, UDT, and OUD care were associated with UDT.

Indexed as

BuprenorphineOpioid-Related DisordersDelivery of Health CareHumansMedicaidOpiate Substitution TreatmentUnited StatesBuprenorphineBuprenorphineDrug testingMedicaidOpioid use disorderOverdoseUrinalysis

Identifiers

PMID37413960
PMCPMC10529442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.