Evidence map›Paper›PMID 37410916›Full record

ArticleDatabase : the journal of biological databases and curation2023

VariantHunter: a method and tool for fast detection of emerging SARS-CoV-2 variants.

Pietro Pinoli, Arif Canakoglu, Stefano Ceri, Matteo Chiara, Erika Ferrandi, Luca Minotti, Anna Bernasconi

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Life (Basel, Switzerland) · 2026
    Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pietro PinoliDepartment of Electronics, Information, and Bioengineering, Politecnico di Milano, Via Ponzio 34/5, Milan 20133, Italy.ORCID 0000-0001-9786-2851
Arif CanakogluDepartment of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 28, Milan 20122, Italy.ORCID 0000-0003-4528-6586
Stefano CeriDepartment of Electronics, Information, and Bioengineering, Politecnico di Milano, Via Ponzio 34/5, Milan 20133, Italy.ORCID 0000-0003-0671-2415
Matteo ChiaraDepartment of Biosciences, University of Milan, Via Celoria 26, Milan 20133, Italy.ORCID 0000-0003-3983-4961
Erika FerrandiDepartment of Biosciences, University of Milan, Via Celoria 26, Milan 20133, Italy.ORCID 0000-0002-2968-8350
Luca MinottiDepartment of Electronics, Information, and Bioengineering, Politecnico di Milano, Via Ponzio 34/5, Milan 20133, Italy.
Anna BernasconiDepartment of Electronics, Information, and Bioengineering, Politecnico di Milano, Via Ponzio 34/5, Milan 20133, Italy.ORCID 0000-0001-8016-5750

Funding

Next Generation EU Program PNRR-PE-AI FAIR
6 · The paper itself

Abstract

With the progression of the COVID-19 pandemic, large datasets of SARS-CoV-2 genome sequences were collected to closely monitor the evolution of the virus and identify the novel variants/strains. By analyzing genome sequencing data, health authorities can 'hunt' novel emerging variants of SARS-CoV-2 as early as possible, and then monitor their evolution and spread. We designed VariantHunter, a highly flexible and user-friendly tool for systematically monitoring the evolution of SARS-CoV-2 at global and regional levels. In VariantHunter, amino acid changes are analyzed over an interval of 4 weeks in an arbitrary geographical area (continent, country, or region); for every week in the interval, the prevalence is computed and changes are ranked based on their increase or decrease in prevalence. VariantHunter supports two main types of analysis: lineage-independent and lineage-specific. The former considers all the available data and aims to discover new viral variants. The latter evaluates specific lineages/viral variants to identify novel candidate designations (sub-lineages and sub-variants). Both analyses use simple statistics and visual representations (diffusion charts and heatmaps) to track viral evolution. A dataset explorer allows users to visualize available data and refine their selection. VariantHunter is a web application free to all users. The two types of supported analysis (lineage-independent and lineage-specific) allow user-friendly monitoring of the viral evolution, empowering genomic surveillance without requiring any computational background. Database URL http://gmql.eu/variant_hunter/.

Indexed as

COVID-19SARS-CoV-2Chromosome MappingHumansPandemics

Identifiers

PMID37410916
PMCPMC10325486

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.