ArticleJournal of applied physiology (Bethesda, Md. : 1985)2023
Age alters the thermoregulatory responses to extreme heat exposure with accompanying activities of daily living.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Thermoregulation and Heat Stroke Prevention in Older Adults: Advances in Emerging Technologies and Interventions.Sensors (Basel, Switzerland) · 2025Pooled it
- Meta-analysis of heat-induced changes in cardiac function from over 400 laboratory-based heat exposure studies.Nature communications · 2025Pooled it
- Low-energy cooling strategies modulate biomarkers of kidney injury risk in older adults exposed to very hot and dry heat.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Trial
- Evaluating low-energy cooling strategies on thermal and cardiac strain in older adults exposed to very hot and dry heat with accompanying activities of daily living.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Trial
- Effects of Daylong Exposure to Indoor Overheating on Thermal and Cardiovascular Strain in Older Adults: A Randomized Crossover Trial.Environmental health perspectives · 2024Trial
- Identifying the Optimal Heat Exposure Metric for Predicting the Physiological Response to Dry or Humid Heat Stress in Young and Older Adults: A Randomized Controlled Study.Environmental health perspectives · 2024Trial
- Endoscopic sympathectomy impairs forearm cutaneous vascular conductance and sweating responses during passive whole body heat stress.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Climate Change and Heat-related Illness in Older Adults: Implications for Emergency Medicine.The western journal of emergency medicine · 2026Review
- Spatial Heterogeneity in Heat-Related Mortality in the Valencian Region: Implications for Climate Adaptation Beyond Administrative Boundaries.GeoHealth · 2026Article
- Body Composition and Thermographic Asymmetry in Older Adults: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Attributing heatwave mortality to human-induced climate change in Greece: a case-crossover and attribution analysis for 2000-2019.Environmental health : a global access science source · 2026Article
- Emergency Department Presentations During Dry and Humid Heatwaves: A Case-Crossover Study in the Northern Territory, Australia.GeoHealth · 2026Article
- The physiology of survival: Heat.Experimental physiology · 2026Article
- Approach to Low Body Temperature or Mild Hypothermia in the Geriatric Population: A Narrative Review.Journal of clinical medicine research · 2026Review
- Association of left ventricular end-diastolic volume with core temperature and heart rate during very hot and dry heat stress in older adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Article
- Rethinking biological resilience of older adults under climate change: an integrative perspective from planetary health and cultural ethics.Frontiers in physiology · 2026Article
- Article
- Brief extreme passive heat exposure leads to elevated biomarkers of systemic inflammation and acute kidney injury in older vs young adults.European journal of applied physiology · 2025Article
- Pulmonary function responses to extreme heat exposure in younger and older adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Heat Tolerance in Older Adults: A Systematic Review of Thermoregulation, Vulnerability, Environmental Change, and Health Outcomes.Healthcare (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Older adults are at greater risk for heat-related morbidity and mortality, due in part to age-related reductions in heat dissipating capabilities. Previous studies investigating the impact of age on responses to heat stress used approaches that lack activities of daily living and therefore may not accurately depict the thermal/physiological strain that would occur during actual heatwaves. We sought to compare the responses of young (18-39 yr) and older (≥65 yr) adults exposed to two extreme heat simulations. Healthy young (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.