Evidence map›Paper›PMID 37410814›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

The ubiquitin-protein ligase MIEL1 localizes to peroxisomes to promote seedling oleosin degradation and lipid droplet mobilization.

Melissa S Traver, Bonnie Bartel

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Heterogeneity, dynamics and organelle interactions of lipid droplets.Nature reviews. Molecular cell biology · 2026
    Review
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  16. Molecular Machinery of Lipid Droplet Degradation and Turnover in Plants.International journal of molecular sciences · 2023
    Review
  17. Profile of Bonnie Bartel.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Melissa S TraverDepartment of Biosciences, Biochemistry and Cell Biology Program, Rice University, Houston, TX 77005.ORCID 0000-0001-6366-5737
Bonnie BartelDepartment of Biosciences, Biochemistry and Cell Biology Program, Rice University, Houston, TX 77005.ORCID 0000-0002-6367-346X
Rice University · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
Peroxisome biogenesis, dynamics, and degradation - Administrative SupplementR35GM130338 · NIGMS · RICE UNIVERSITY · PI Bonnie Bartel · 2019 to 2026
$3.3M
NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NIGMS NIH HHS R01 GM129325NIGMS NIH HHS R35 GM130338
6 · The paper itself

Abstract

Lipid droplets are organelles conserved across eukaryotes that store and release neutral lipids to regulate energy homeostasis. In oilseed plants, fats stored in seed lipid droplets provide fixed carbon for seedling growth before photosynthesis begins. As fatty acids released from lipid droplet triacylglycerol are catabolized in peroxisomes, lipid droplet coat proteins are ubiquitinated, extracted, and degraded. In

Indexed as

ArabidopsisArabidopsis ProteinsHumansLipid DropletsLipid MobilizationPeroxisomesSeedlingsTranscription FactorsTumor Suppressor Protein p53Ubiquitin-Protein LigasesArabidopsis ProteinsMIEL1 protein, ArabidopsisMYB30 protein, ArabidopsisTranscription FactorsTumor Suppressor Protein p53Ubiquitin-Protein LigasesArabidopsis thalianaE3 ubiquitin ligaselipid dropletperoxisomePIRH2

Identifiers

PMID37410814
PMCPMC10629534
OpenAlexW4383313931

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.