Evidence map›Paper›PMID 37410714›Full record

ArticlePLoS neglected tropical diseases2023

Whole genome sequencing and phylogenetic characterisation of rabies virus strains from Moldova and north-eastern Romania.

Mihaela Anca Dascalu, Evelyne Picard-Meyer, Emmanuelle Robardet, Alexandre Servat, Serghei Arseniev, Oxana Groza, Nicolae Starciuc, Vlad Vuta, Florica Barbuceanu, Oana Irina Tanase and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Rabies Reemergence, Central Europe, 2022-2024.Emerging infectious diseases · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Mihaela Anca DascaluDepartment of Public Health, Faculty of Veterinary Medicine, Iasi University of Life Sciences "Ion Ionescu de la Brad", Mihail Sadoveanu Alley, Romania.ORCID 0000-0003-1233-3585
Evelyne Picard-MeyerANSES, Nancy Laboratory for Rabies and Wildlife, WHO Collaborating Centre for Research and Management in Zoonoses Control, OIE Reference Laboratory for Rabies, European Union Reference Laboratory for Rabies, European Union Reference Laboratory for Rabies Serology, Technopôle Agricole et Vétérinaire, Malzéville, France.
Emmanuelle RobardetANSES, Nancy Laboratory for Rabies and Wildlife, WHO Collaborating Centre for Research and Management in Zoonoses Control, OIE Reference Laboratory for Rabies, European Union Reference Laboratory for Rabies, European Union Reference Laboratory for Rabies Serology, Technopôle Agricole et Vétérinaire, Malzéville, France.
Alexandre ServatANSES, Nancy Laboratory for Rabies and Wildlife, WHO Collaborating Centre for Research and Management in Zoonoses Control, OIE Reference Laboratory for Rabies, European Union Reference Laboratory for Rabies, European Union Reference Laboratory for Rabies Serology, Technopôle Agricole et Vétérinaire, Malzéville, France.
Serghei ArsenievRepublican Center of Veterinary Diagnostic, Chisinau, Moldova.
Oxana GrozaRepublican Center of Veterinary Diagnostic, Chisinau, Moldova.
Nicolae StarciucFaculty of Veterinary Medicine, State Agrarian University, Chisinau, Moldova.
Vlad VutaInstitute for Diagnosis and Animal Health, OIE Reference Laboratory for Rabies, Bucharest, Romania; University of Agronomic Study and Veterinary Medicine, Faculty of Veterinary Medicine, Bucharest, Romania.
Florica BarbuceanuInstitute for Diagnosis and Animal Health, OIE Reference Laboratory for Rabies, Bucharest, Romania; University of Agronomic Study and Veterinary Medicine, Faculty of Veterinary Medicine, Bucharest, Romania.
Oana Irina TanaseDepartment of Public Health, Faculty of Veterinary Medicine, Iasi University of Life Sciences "Ion Ionescu de la Brad", Mihail Sadoveanu Alley, Romania.
Florentina Daraban BocanetiDepartment of Public Health, Faculty of Veterinary Medicine, Iasi University of Life Sciences "Ion Ionescu de la Brad", Mihail Sadoveanu Alley, Romania.
Helene QuenaultANSES, Nancy Ploufragan-Plouzané-Niort Laboratory, Viral Genetics and Biosafety Unit, Technopôle Agricole et Vétérinaire, Malzéville, France.
Edouard HirchaudANSES, Nancy Ploufragan-Plouzané-Niort Laboratory, Viral Genetics and Biosafety Unit, Technopôle Agricole et Vétérinaire, Malzéville, France.
Yannick BlanchardANSES, Nancy Ploufragan-Plouzané-Niort Laboratory, Viral Genetics and Biosafety Unit, Technopôle Agricole et Vétérinaire, Malzéville, France.
Elena VelescuDepartment of Public Health, Faculty of Veterinary Medicine, Iasi University of Life Sciences "Ion Ionescu de la Brad", Mihail Sadoveanu Alley, Romania.
Florence CliquetANSES, Nancy Laboratory for Rabies and Wildlife, WHO Collaborating Centre for Research and Management in Zoonoses Control, OIE Reference Laboratory for Rabies, European Union Reference Laboratory for Rabies, European Union Reference Laboratory for Rabies Serology, Technopôle Agricole et Vétérinaire, Malzéville, France.
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail · FR"Ion Ionescu de la Brad" Iasi University of Life Sciences · ROUniversity of Agronomic Sciences and Veterinary Medicine of Bucharest · ROState Agrarian University of Moldova · MD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRabies is the oldest fatal zoonotic disease recognised as a neglected tropical disease and is caused by an RNA virus belonging to the genus Lyssavirus, family Rhabdoviridae. METHODOLOGY/PRINCIPAL

findingsA deep molecular analysis was conducted on full-length nucleoprotein (N) gene and whole genome sequences of rabies virus from 37 animal brain samples collected between 2012 and 2017 to study the circulation of rabies virus (RABV) variants. The overall aim was to better understand their distribution in Moldova and north-eastern Romania. Both Sanger and high throughput sequencing on Ion Torrent and Illumina platforms were performed. Phylogenetic analysis of the RABV sequences from both Moldova and Romania revealed that all the samples (irrespective of the year of isolation and the species) belonged to a single phylogenetic group: north-eastern Europe (NEE), clustering into three assigned lineages: RO#5, RO#6 and RO#7. CONCLUSIONS/SIGNIFICANCE: High throughput sequencing of RABV samples from domestic and wild animals was performed for the first time for both countries, providing new insights into virus evolution and epidemiology in this less studied region, expanding our understanding of the disease.

Indexed as

RabiesRabies virusAnimalsMoldovaPhylogenyRomaniaWhole Genome Sequencing

Identifiers

PMID37410714
PMCPMC10325106
OpenAlexW4383340193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.