Evidence map›Paper›PMID 37410383›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2023

Estimated incubation period distributions of mpox using cases from two international European festivals and outbreaks in a club in Berlin, May to June 2022.

Sarah E McFarland, Ulrich Marcus, Lukas Hemmers, Fuminari Miura, Jesús Iñigo Martínez, Fernando Martín Martínez, Elisa Gil Montalbán, Emilie Chazelle, Alexandra Mailles, Yassoungo Silue and 18 more

Erratum issuedAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Rapid spread of MPXV clade Ib with high genetic relatedness among men who have sex with men, Berlin, Germany, week 50 2025 up to week 10 2026.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Factors potentially contributing to the decline of the mpox outbreak in the Netherlands, 2022 and 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Observational
  14. Article
  15. Article
  16. Letter to the editor: Bias in the vaccine effectiveness estimates of one-dose post-exposure prophylaxis against mpox.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors.

Sarah E McFarlandUnit for Surveillance and Epidemiology of Infectious Diseases, State Office for Health and Social Affairs (SOHSA), Berlin, Germany.
Ulrich MarcusUnit 'HIV/AIDS, STI and Blood-borne Infections', Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Lukas HemmersUnit for Surveillance and Epidemiology of Infectious Diseases, State Office for Health and Social Affairs (SOHSA), Berlin, Germany.
Fuminari MiuraCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Jesús Iñigo MartínezDirectorate General of Public Health, Regional Ministry of Health of Madrid, Madrid, Spain.
Fernando Martín MartínezDirectorate General of Public Health, Regional Ministry of Health of Madrid, Madrid, Spain.
Elisa Gil MontalbánDirectorate General of Public Health, Regional Ministry of Health of Madrid, Madrid, Spain.
Emilie ChazelleSanté publique France, the French national public health agency, Saint-Maurice, France.
Alexandra MaillesSanté publique France, the French national public health agency, Saint-Maurice, France.
Yassoungo SilueSanté publique France, the French national public health agency, Paris area regional office, Saint-Denis, France.
Naïma HammamiDepartment of Infectious Disease Prevention and Control, Agency for Care and Health, Flemish Region, Brussels, Belgium.
Amaryl LecompteDepartment of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
Nicolas LedentDepartment of Infectious Disease Prevention and Control, Common Community Commission, Brussels-Capital Region, Brussels, Belgium.
Wim Vanden BergheDepartment of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
Laurens LiesenborghsDepartment of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Dorien Van den BosscheDepartment of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Paul R ClearyField Service North West, UK Health Security Agency, Liverpool, United Kingdom.
Jacco WallingaDepartment of Biomedical Data Sciences, Leiden University Medical Center (LUMC), Leiden, the Netherlands.
Eve P RobinsonHealth Protection Surveillance Centre, Dublin, Ireland.
Tone Bjordal JohansenDepartment of Infection Control and Preparedness, Norwegian Institute of Public Health, Oslo, Norway.
Antra BormaneDiseases Surveillance and Immunization Unit, Centre for Disease Prevention and Control, Riga, Latvia.
Tanya MelilloInfectious Disease Prevention and Control Unit, HPDP, Department for Health Regulation, Ministry of Health, Gwardamangia, Malta.
Cornelia SeidlBavarian Health and Food Safety Authority (LGL), Munich, Germany.
Liza CoyerBavarian Health and Food Safety Authority (LGL), Munich, Germany.
Ronja BobergState Office for Occupational Safety, Consumer Protection and Health, Brandenburg, Germany.
Annette JurkeNRW Centre for Health, North Rhine-Westphalia, Bochum, Germany.
Dirk WerberUnit for Surveillance and Epidemiology of Infectious Diseases, State Office for Health and Social Affairs (SOHSA), Berlin, Germany.
Alexander BartelUnit for Surveillance and Epidemiology of Infectious Diseases, State Office for Health and Social Affairs (SOHSA), Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundSince May 2022, an mpox outbreak affecting primarily men who have sex with men (MSM) has occurred in numerous non-endemic countries worldwide. As MSM frequently reported multiple sexual encounters in this outbreak, reliably determining the time of infection is difficult; consequently, estimation of the incubation period is challenging.AimWe aimed to provide valid and precise estimates of the incubation period distribution of mpox by using cases associated with early outbreak settings where infection likely occurred.MethodsColleagues in European countries were invited to provide information on exposure intervals and date of symptom onset for mpox cases who attended a fetish festival in Antwerp, Belgium, a gay pride festival in Gran Canaria, Spain or a particular club in Berlin, Germany, where early mpox outbreaks occurred. Cases of these outbreaks were pooled; doubly censored models using the log-normal, Weibull and Gamma distributions were fitted to estimate the incubation period distribution.ResultsWe included data on 122 laboratory-confirmed cases from 10 European countries. Depending on the distribution used, the median incubation period ranged between 8 and 9 days, with 5th and 95th percentiles ranging from 2 to 3 and from 20 to 23 days, respectively. The shortest interval that included 50% of incubation periods spanned 8 days (4-11 days).ConclusionCurrent public health management of close contacts should consider that in approximately 5% of cases, the incubation period exceeds the commonly used monitoring period of 21 days.

Indexed as

Homosexuality, MaleMpox, MonkeypoxBerlinDisease OutbreaksHolidaysHumansInfectious Disease Incubation PeriodMaleSexual and Gender MinoritiesEuropeGermanyincubation periodmonkeypox virusmpoxMPXV

Identifiers

PMID37410383
PMCPMC10370040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.