Evidence map›Paper›PMID 37410340›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023

Quality of life in the year after new diagnosis with advanced prostate cancer for Black and White individuals living in the US.

Emily M Rencsok, Natalie Slopen, Karen Autio, Alicia Morgans, Lawrence McSwain, Pedro Barata, Heather H Cheng, Robert Dreicer, Elisabeth Heath, Rana R McKay and 13 more

Open access · greenAbstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Bridging the Gap: Enhancing Prostate Cancer Survivorship and Advocacy Among Ethnically Diverse Black Men Through Community Town Halls.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Article
  3. Article
  4. Article
  5. Health-related quality of life in ethnically diverse Black prostate cancer survivors: a convergent parallel mixed-methods approach.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 16 institutions in 2 countries.

Emily M RencsokDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. emily_rencsok@hms.harvard.edu.
Natalie SlopenDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Karen AutioMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Alicia MorgansDana-Farber Cancer Institute, Boston, MA, USA.
Lawrence McSwain, Durham, NC, USA.
Pedro BarataSection of Hematology and Oncology, Tulane University School of Medicine, New Orleans, LA, USA.
Heather H ChengDivision of Medical Oncology, University of Washington, Seattle, WA, USA.
Robert DreicerUniversity of Virginia Cancer Center, Charlottesville, VA, USA.
Elisabeth HeathKarmanos Cancer Institute, Detroit, MI, USA.
Rana R McKayDepartment of Oncology, University of California San Diego Moores Cancer Center, La Jolla, CA, USA.
Mark PomerantzDana-Farber Cancer Institute, Boston, MA, USA.
Dana RathkopfMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Scott TagawaDivision of Hematology and Medical Oncology, Weill Cornell Medical Center, New York, NY, USA.
Young E WhangDepartment of Medicine, Division of Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Camille RaginFox Chase Cancer Center, Philadelphia, PA, USA.
Folakemi T OdedinaMayo Clinic Comprehensive Cancer Center, Jacksonville, FL, USA.
Daniel J GeorgeDuke Cancer Institute, Durham, NC, USA.
Philip W KantoffMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Jacob VinsonProstate Cancer Clinical Trials Consortium (PCCTC), New York, NY, USA.
Paul VillantiMovember Foundation, Melbourne, Australia.
Sebastien Haneuse *Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Lorelei A Mucci *Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
IRONMAN Registry
Harvard University · USDana-Farber Cancer Institute · USMemorial Sloan Kettering Cancer Center · USConvergent Science (United States) · USCornell University · USDuke Cancer InstituteFox Chase Cancer Center · USMovember Foundation · AUProstate Cancer Clinical Trials Consortium · USProstate Cancer Foundation · USThe Barbara Ann Karmanos Cancer Institute · USUniversity Hospitals Seidman Cancer Center · USUniversity of California, San Diego · USUniversity of North Carolina at Chapel Hill · USUniversity of Virginia · USUniversity of Washington Medical Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
Racial disparities in advanced prostate cancer care: An analysis of treatment patterns and patient experienceF30CA264965 · NCI · HARVARD MEDICAL SCHOOL · PI RENCSOK, EMILY MAE · 2022 to 2025
$177k
NCI NIH HHS F30 CA264965NCI NIH HHS F30CA264965NCI NIH HHS P30 CA008748NIGMS NIH HHS T32 GM007753NIGMS NIH HHS T32GM007753NIGMS NIH HHS T32 GM144273NIGMS NIH HHS T32GM144273
6 · The paper itself

Abstract

purposeTo assess differences in baseline and longitudinal quality of life among Black and White individuals in the US with advanced prostate cancer.

methodsSecondary analysis of data from the International Registry for Men with Advanced Prostate Cancer (IRONMAN) including US participants newly diagnosed with advanced prostate cancer and identifying their race as Black or White from 2017 to 2023. Participants completed the EORTC QLQ-C30 Quality of Life (QoL) Survey at study enrollment and every 3 months thereafter for up to 1 year of follow-up reporting 15 scale scores ranging from 0 to 100 (higher functioning and lower symptom scores represent better quality of life). Linear mixed effects models with race and month of questionnaire completion were fit for each scale, and model coefficients were used to assess differences in baseline and longitudinal QoL by race.

resultsEight hundred and seventy-nine participants were included (20% identifying as Black) at 38 US sites. Compared to White participants at baseline, Black participants had worse constipation (mean 6.3 percentage points higher; 95% CI 2.9-9.8), financial insecurity (5.7 (1.4-10.0)), and pain (5.1 (0.9-9.3)). QoL decreased over time similarly by race; most notably, role functioning decreased by 0.7 percentage points (95% CI -0.8, -0.5) per month.

conclusionThere are notable differences in quality of life at new diagnosis of advanced prostate cancer for Black and White individuals, and quality of life declines similarly in the first year for both groups. Interventions that address specific aspects of quality of life in these patients could meaningfully improve the overall survivorship experience.

Indexed as

Prostatic NeoplasmsQuality of LifeBlack or African AmericanHumansMalePainWhiteEpidemiologyProstate cancerQuality of lifeRacial disparities

Identifiers

PMID37410340
PMCPMC10711502
OpenAlexW4383301602

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.