Evidence map›Paper›PMID 37410293›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Negative Ion-Mode N-Glycan Mass Spectrometry Imaging by MALDI-2-TOF-MS.

Jens Soltwisch, Bram Heijs

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Jens SoltwischCenter for Proteomics & Metabolomics, Leiden University Medical Center, Leiden, The Netherlands.
Bram HeijsCenter for Proteomics & Metabolomics, Leiden University Medical Center, Leiden, The Netherlands. B.P.A.M.Heijs@lumc.nl.
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matrix-assisted laser desorption/ionization mass spectrometry imaging with laser-induced postionization (MALDI-2-MSI) has proven a powerful tool for the in situ analysis of N-linked glycosylation, or N-glycans, directly from clinical tissue samples. Here we describe a sample preparation protocol for the analysis of N-glycans from formalin-fixed, paraffin-embedded tissue sections.

Indexed as

Diagnostic ImagingPolysaccharidesGlycosylationParaffin EmbeddingSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationPolysaccharidesLaser-induced postionizationMALDI-2Mass spectrometry imagingMatrix-assisted laser desorption/ionizationN-Linked glycosylationOligosaccharidesOn-tissue enzymatic digestion

Identifiers

PMID37410293
OpenAlexW4383302432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.