Evidence map›Paper›PMID 37410165›Full record

ArticleUrologie (Heidelberg, Germany)2023

[First-line treatment of metastatic renal cell carcinoma].

Andreas Bruchbacher, Christopher Netsch, Andreas J Gross

Abstract readEnglish Abstract
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In one paragraph

Article in Urologie (Heidelberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andreas BruchbacherAbteilung für Urologie, Asklepios Klink Barmbek, Rübenkamp, 22307, Hamburg, Deutschland. andreas_bruchbacher@hotmail.com.
Christopher NetschAbteilung für Urologie, Asklepios Klink Barmbek, Rübenkamp, 22307, Hamburg, Deutschland.
Andreas J GrossAbteilung für Urologie, Asklepios Klink Barmbek, Rübenkamp, 22307, Hamburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years the first-line treatment of metastatic renal cell carcinoma was revolutionized by the introduction of checkpoint inhibitors (CPI). Within a few years several combined modality treatments with CPI and tyrosine kinase inhibitors (TKI) have proven to be effective and safe in the application. According to the guidelines, up to five different combined modality treatments can now be considered, depending on the risk profile. Based on the current data situation, a direct distinction between the treatments cannot be made as no comparative studies are available. Therefore, the decision for a particular treatment is often guided by individual factors. In particular, a clear processing of the patient with the respective risk factors and tumor identity is essential. Hence, it is all the more important to discuss complex cases in an interdisciplinary tumor board.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsCombined Modality TherapyHumansImmunotherapyProtein Kinase InhibitorsProtein Kinase InhibitorsCheckpoint inhibitorsCombined modality treatmentKidney neoplasmsNeoplasm metastasisTyrosine protein kinase inhibitors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.