Evidence map›Paper›PMID 37410138›Full record

ReviewApplied microbiology and biotechnology2023

Mushroom β-glucans: application and innovation for food industry and immunotherapy.

Thaynã Gonçalves Timm, Tania Maria Costa, Michele Debiasi Alberton, Cristiane Vieira Helm, Lorena Benathar Ballod Tavares

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Study on the Enrichment Effect ofMicroorganisms · 2025
    Article
  3. Article
  4. Article
  5. Possibilities of Using the NewFoods (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Thaynã Gonçalves TimmEnvironmental Engineering Graduate Program, Regional University of Blumenau, Blumenau, Santa Catarina, Brazil. ttimm@furb.br.ORCID http://orcid.org/0000-0001-5683-3536
Tania Maria CostaUniversity Center UniSENAI, Blumenau, Santa Catarina, Brazil.ORCID http://orcid.org/0000-0001-7270-3264
Michele Debiasi AlbertonPharmaceutical Science Department, Regional University of Blumenau, Blumenau, Santa Catarina, Brazil.ORCID http://orcid.org/0000-0003-3490-9936
Cristiane Vieira HelmBrazilian Agricultural Research Corporation, Research Center of Forestry - Embrapa Florestas, Colombo, Paraná, Brazil.ORCID http://orcid.org/0000-0002-7518-9069
Lorena Benathar Ballod TavaresEnvironmental Engineering Graduate Program, Regional University of Blumenau, Blumenau, Santa Catarina, Brazil.ORCID http://orcid.org/0000-0001-7633-8196
Universidade Regional de Blumenau · BRBrazilian Agricultural Research Corporation · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico Grant 305880/2020-9 - CNPq N° 02/2020Conselho Nacional de Desenvolvimento Científico e Tecnológico MCTI/CNPq Nº 20/2017Coordenação de Aperfeiçoamento de Pessoal de Nível Superior DS 88887.490173/2020-00Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001
6 · The paper itself

Abstract

Among the most important sources of β-glucans are edible and medicinal mushrooms. These molecules are components of the cellular wall of basidiomycete fungi (mushrooms) and can be extracted even from the basidiocarp as the mycelium and its cultivation extracts or biomasses. Mushroom β-glucans are recognized by their potential effects as immunostimulants and immunosuppressants. They are highlighted as anticholesterolemic, anti-inflammatory, adjuvant in diabetes mellitus, mycotherapy for cancer treatment, as well as adjuvants for COVID-19 vaccines. Due to their relevance, several techniques of β-glucans extraction, purification, and analysis have already been described. Despite the previous knowledge of β-glucans' benefits for human nutrition and health, the main information about this topic refers to the molecular identification, properties, and benefits, as well as their synthesis and action on cells. Studies on biotechnology industry applications (product development) and the registered products of β-glucans from mushrooms are still limited and more common for feed and healthcare. In this context, this paper reviews the biotechnological production of food products containing β-glucans from basidiomycete fungi, focusing on food enrichment, and presents a new perspective on fungi β-glucans' use as potential immunotherapy agents. KEY POINTS: • Mushrooms' β-glucans for product development in the biotechnology industry • Biotechnological production of food products containing mushrooms' β-glucans • Basidiomycete fungi β-glucans are used as potential immunotherapy agents.

Indexed as

AgaricalesBasidiomycotabeta-GlucansCOVID-19Adjuvants, ImmunologicCOVID-19 VaccinesFood IndustryHumansImmunotherapyAdjuvants, Immunologicbeta-GlucansCOVID-19 VaccinesBioactive propertiesFood enrichmentMycotherapyProduct development

Identifiers

PMID37410138
OpenAlexW4383302821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.