Evidence map›Paper›PMID 37410076›Full record

ArticleeLife2023

A simple mechanism for integration of quorum sensing and cAMP signalling in

Lucas M Walker, James R J Haycocks, Julia C Van Kessel, Triana N Dalia, Ankur B Dalia, David C Grainger

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Actuation of CRP activating region 3 by formylation modulates theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. A 3'UTR-derived small RNA modulates the life cycle of the cholera toxin-encoding filamentous phage, CTXϕ.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Review
  4. Light-activated cAMP signaling controls sodium-driven motility inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Single-cell RNA-seq reveals a key role forFrontiers in microbiology · 2025
    Article
  11. Transcription activation inEcoSal Plus · 2024
    Review
  12. Article
  13. A comparative genomic and phenotypic study ofMicrobiology (Reading, England) · 2024
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Lucas M WalkerSchool of Biosciences, University of Birmingham, Edgbaston, United Kingdom.
James R J HaycocksSchool of Biosciences, University of Birmingham, Edgbaston, United Kingdom.
Julia C Van KesselDepartment of Biology, Indiana University, Bloomington, United States.ORCID 0000-0002-1612-2403
Triana N DaliaDepartment of Biology, Indiana University, Bloomington, United States.
Ankur B DaliaDepartment of Biology, Indiana University, Bloomington, United States.
David C GraingerSchool of Biosciences, University of Birmingham, Edgbaston, United Kingdom.ORCID 0000-0003-3375-5154
Indiana University · USUniversity of Birmingham · GB

Funding

Mechanisms and regulation of horizontal gene transfer by natural transformation in Vibrio choleraeR35GM128674 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Ankur Dalia · 2018 to 2026
$3.8M
Biotechnology and Biological Sciences Research Council BB/M01116X/1Biotechnology and Biological Sciences Research Council BB/N005961/1Biotechnology and Biological Sciences Research Council project reference 1898542NIGMS NIH HHS R35 GM128674NIH HHS R35GM128674
6 · The paper itself

Abstract

Many bacteria use quorum sensing to control changes in lifestyle. The process is regulated by microbially derived 'autoinducer' signalling molecules, that accumulate in the local environment. Individual cells sense autoinducer abundance, to infer population density, and alter their behaviour accordingly. In

Indexed as

Vibrio choleraeBacterial ProteinsCyclic AMP Receptor ProteinGene Expression Regulation, BacterialHumansQuorum SensingRepressor ProteinsTranscription FactorsBacterial ProteinsCyclic AMP Receptor ProteinRepressor ProteinsTranscription Factorsbacteriachromosomescyclic ampgene expressionquorum sensingtranscriptionVibrio cholerae

Identifiers

PMID37410076
PMCPMC10328515
OpenAlexW4362617703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.