Evidence map›Paper›PMID 37409739›Full record

ArticlePharmaceutical biology2023

Characterization of potentially health-promoting constituents in sea fennel (

Antonietta Maoloni, Teresa Pirker, Eva-Maria Pferschy-Wenzig, Lucia Aquilanti, Rudolf Bauer

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecules (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Identification of Polyphenols in Sea Fennel (Foods (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Sea Fennel (Molecules (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Antonietta MaoloniDipartimento di Scienze Agrarie, Alimentari ed Ambientali, Università Politecnica delle Marche, Ancona, Italy.
Teresa PirkerInstitute of Pharmaceutical Sciences, University of Graz, Graz, Austria.
Eva-Maria Pferschy-WenzigInstitute of Pharmaceutical Sciences, University of Graz, Graz, Austria.
Lucia AquilantiDipartimento di Scienze Agrarie, Alimentari ed Ambientali, Università Politecnica delle Marche, Ancona, Italy.
Rudolf BauerInstitute of Pharmaceutical Sciences, University of Graz, Graz, Austria.
University of Graz · ATMarche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextSea fennel (

objectiveThis study aimed at the characterization of sea fennel secondary metabolites, focusing on the phenolic fraction. MATERIALS AND

methodsSamples of whole sprouts, sole leaves and sole stems were subjected to accelerated solvent extraction with methanol, and the resulting extracts were analyzed by high‑performance thin‑layer chromatography, high-performance liquid chromatography, and liquid chromatography coupled with diode array detection and high-resolution mass spectrometry (LC-DAD-HRMS).

resultsHPTLC and HPLC analyses of sea fennel extracts showed similar chromatographic profiles among the tested samples, and the prevalence of chlorogenic acid within the phenolic fraction was verified. Ten hydroxycinnamic acids, including neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, isochlorogenic acid B, isochlorogenic acid A and isochlorogenic acid C, 11 flavonoid glycosides, e.g., rutin, hyperoside, isoquercitrin, two triterpene saponins and two hydroxylated fatty acids, were detected and annotated DISCUSSION AND

conclusionsThe use of accelerated solvent extraction and LC-DAD-HRMS for the characterization of sea fennel secondary metabolites allowed the annotation of seven compounds newly detected in sea fennel, including triterpene saponins and hydroxylated fatty acids.

Indexed as

ApiaceaeFoeniculumSaponinsTriterpenesChlorogenic AcidChromatography, High Pressure LiquidHumansPlant ExtractsSolventsChlorogenic AcidPlant ExtractsSaponinsSolventsTriterpenesAccelerated solvent extractionchlorogenic acidhydroxylated fatty acidsLC/MStriterpene saponins

Identifiers

PMID37409739
PMCPMC10327526
OpenAlexW4383302269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.