Evidence map›Paper›PMID 37409312›Full record

ArticleJAAD international2023

Characteristics and treatment pathways in pediatric and adult hidradenitis suppurativa: An examination using real world data.

Jill Hardin, Rupa Makadia, Shawn Black, Irene Lara-Corrales, Lucia Z Diaz, Joslyn S Kirby, Cynthia M C DeKlotz

Open access · goldAbstract read
In one paragraph

Article in JAAD international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Jill HardinJanssen Research and Development, Raritan, New Jersey.
Rupa MakadiaJanssen Research and Development, Raritan, New Jersey.
Shawn BlackJanssen Research and Development, Spring House, Pennsylvania.
Irene Lara-CorralesThe Hospital for Sick Children, Toronto, Ontario, Canada.
Lucia Z DiazDepartment of Pediatrics, The University of Texas at Austin, Austin, Texas.
Joslyn S KirbyDepartment of Dermatology, Pennsylvania State University, Hershey, Pennsylvania.
Cynthia M C DeKlotzJanssen Research and Development, Spring House, Pennsylvania.
Janssen (United States) · USHospital for Sick Children · CAPennsylvania State University · USThe University of Texas at Austin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hidradenitis suppurativa (HS) is a chronic, debilitating, inflammatory disease. Contemporaneous real-world data can be used to elucidate the clinical treatment of pediatric patients and how treatment strategies compare with adult hidradenitis suppurativa patients. Objective: The objective of this study is to evaluate clinical and treatment characteristics of pediatric and adult HS patients. Methods: HS adult and pediatric patients were identified in 3 the United States administrative claims databases during the study period between 2016 to 2021. Patients were required to have 2 diagnostic codes for HS and have at least 365 days of prior observation time to the first HS diagnosis. Results: Pediatric and adult HS treatments were similar. The proportions of subjects treated with topical and oral antibiotic or oral antibiotic alone or topical medication alone or surgery alone covered 90% of the treated pediatric subjects and 91% of treated adult subjects. The remaining proportion of subjects received other treatment combinations. Limitations: The databases represent subjects with commercial or government insurance coverage and thus do not necessarily represent the broader US population. The databases do not capture information about medications obtained without insurance. Conclusions: Although subtle differences exist, this study confirms that topical and systemic therapeutic treatment of HS in adults and adolescents is very similar.

Indexed as

epidemiologyhidradenitis suppurativamedical dermatologyobservational datapediatric dermatologypharmacoepidemiologyreal-world data

Identifiers

PMID37409312
PMCPMC10319301
OpenAlexW4381253632

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.