Evidence map›Paper›PMID 37409240›Full record

ArticleReproductive medicine and biology

Therapeutic efficacy of gentle endometrial curettage on antibiotic-resistant chronic endometritis in infertile women.

Keiji Kuroda, Shunsuke Ishiyama, Keisuke Shiobara, Kazuki Nakao, Azusa Moriyama, Hisayo Kataoka, Takashi Horikawa, Yuko Ojiro, Satoru Takamizawa, Koji Nakagawa and 1 more

Open access · goldAbstract read
In one paragraph

Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Keiji KurodaCenter for Reproductive Medicine and Endoscopy Sugiyama Clinic Marunouchi Tokyo Japan.ORCID https://orcid.org/0000-0003-2759-9159
Shunsuke IshiyamaCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.
Keisuke ShiobaraCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.
Kazuki NakaoCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.
Azusa MoriyamaCenter for Reproductive Medicine and Endoscopy Sugiyama Clinic Marunouchi Tokyo Japan.
Hisayo KataokaCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.
Takashi HorikawaCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.
Yuko OjiroCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.
Satoru TakamizawaCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.ORCID https://orcid.org/0000-0002-1103-6856
Koji NakagawaCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.ORCID https://orcid.org/0000-0003-0874-5894
Rikikazu SugiyamaCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To identify the efficacy of endometrial curettage on antibiotic-resistant chronic endometritis (CE) in infertile women. Methods: Of 1580 women with CE, 87 with antibiotic-resistant CE after two to five cycles of antibiotic treatment were recruited between 2019 and 2021. The women who underwent endometrial curettage without applying any force and, in the subsequent menstrual cycle, endometrial sampling for CD138 immunostaining without antibiotic use. Pregnancy outcomes after in vitro fertilization treatment were analyzed in women who did not desire endometrial curettage and in those with cured and persistent CE after endometrial curettage. Results: In 64 women who underwent endometrial curettage, the number of CD138-positive cells decreased from 28.0 ± 35.3 to 7.7 ± 14.0 ( Conclusions: Gentle endometrial curettage for antibiotic-resistant CE significantly decreased the number of CD138-positive cells, resulting in improved pregnancy outcomes regardless of remaining CE. Endometrial curettage is also important as a screening for endometrial malignancy.

Indexed as

antibiotic resistanceCD138chronic endometritisendometrial curettageinfertility

Identifiers

PMID37409240
PMCPMC10318421
OpenAlexW4383111699

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.